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2gat
From Proteopedia
(Difference between revisions)
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==SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF CHICKEN GATA-1 BOUND TO DNA, NMR, REGULARIZED MEAN STRUCTURE== | ==SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF CHICKEN GATA-1 BOUND TO DNA, NMR, REGULARIZED MEAN STRUCTURE== | ||
| - | <StructureSection load='2gat' size='340' side='right'caption='[[2gat | + | <StructureSection load='2gat' size='340' side='right'caption='[[2gat]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2gat]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2gat]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GAT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GAT FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gat OCA], [https://pdbe.org/2gat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gat RCSB], [https://www.ebi.ac.uk/pdbsum/2gat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gat ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gat OCA], [https://pdbe.org/2gat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gat RCSB], [https://www.ebi.ac.uk/pdbsum/2gat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gat ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/GATA1_CHICK GATA1_CHICK] Transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Gallus gallus]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Clore | + | [[Category: Clore GM]] |
| - | [[Category: Gronenborn | + | [[Category: Gronenborn AM]] |
| - | [[Category: Omichinski | + | [[Category: Omichinski JG]] |
| - | [[Category: Starich | + | [[Category: Starich M]] |
| - | [[Category: Tjandra | + | [[Category: Tjandra N]] |
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Current revision
SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF CHICKEN GATA-1 BOUND TO DNA, NMR, REGULARIZED MEAN STRUCTURE
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