7eg6

==Snf5 Finger Helix bound to the nucleosome==

<StructureSection load='7eg6' size='340' side='right'caption='[[7eg6]], [[Resolution|resolution]] 3.10&Aring;' scene=''>

<table><tr><td colspan='2'>[[7eg6]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EG6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EG6 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7eg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7eg6 OCA], [https://pdbe.org/7eg6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7eg6 RCSB], [https://www.ebi.ac.uk/pdbsum/7eg6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7eg6 ProSAT]</span></td></tr>

== Function ==

[https://www.uniprot.org/uniprot/SNF5_YEAST SNF5_YEAST] Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.

==See Also==

*[[Histone 3D structures|Histone 3D structures]]

[[Category: Saccharomyces cerevisiae S288C]]

[[Category: Ye YP]]