7e38

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<StructureSection load='7e38' size='340' side='right'caption='[[7e38]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='7e38' size='340' side='right'caption='[[7e38]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7e38]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7E38 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7E38 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7e38]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sinopodophyllum_hexandrum Sinopodophyllum hexandrum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7E38 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7E38 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene>, <scene name='pdbligand=YTC:(3~{S},4~{S})-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one'>YTC</scene>, <scene name='pdbligand=YTN:(3~{R},4~{R})-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one'>YTN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7e37|7e37]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene>, <scene name='pdbligand=YTC:(3~{S},4~{S})-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one'>YTC</scene>, <scene name='pdbligand=YTN:(3~{R},4~{R})-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one'>YTN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/(-)-deoxypodophyllotoxin_synthase (-)-deoxypodophyllotoxin synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.20.8 1.14.20.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7e38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7e38 OCA], [https://pdbe.org/7e38 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7e38 RCSB], [https://www.ebi.ac.uk/pdbsum/7e38 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7e38 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7e38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7e38 OCA], [https://pdbe.org/7e38 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7e38 RCSB], [https://www.ebi.ac.uk/pdbsum/7e38 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7e38 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/2ODD_SINHE 2ODD_SINHE]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chan, N L]]
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[[Category: Sinopodophyllum hexandrum]]
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[[Category: Chang, W c]]
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[[Category: Chan N-L]]
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[[Category: Chien, T C]]
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[[Category: Chang W-c]]
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[[Category: Wu, M H]]
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[[Category: Chien T-C]]
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[[Category: Biosynthetic protein]]
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[[Category: Wu M-H]]
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[[Category: Non-heme iron/2-oxoglutarate enzyme beta-helix fold deoxypodophyllotoxin biosynthesis carbon-carbon bond formation]]
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Revision as of 16:45, 29 November 2023

Crystal structure of deoxypodophyllotoxin synthase from Sinopodophyllum hexandrum in complex with yatein and succinate

PDB ID 7e38

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