1aih
From Proteopedia
(New page: 200px<br /> <applet load="1aih" size="450" color="white" frame="true" align="right" spinBox="true" caption="1aih, resolution 2.5Å" /> '''CATALYTIC DOMAIN OF ...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1AIH is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ | + | 1AIH is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Haemophilus_phage_hp1 Haemophilus phage hp1]] with SO4 and MG as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Sites: ACA, ACB, ACC and ACD. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1AIH OCA]]. |
==Reference== | ==Reference== | ||
Molecular organization in site-specific recombination: the catalytic domain of bacteriophage HP1 integrase at 2.7 A resolution., Hickman AB, Waninger S, Scocca JJ, Dyda F, Cell. 1997 Apr 18;89(2):227-37. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9108478 9108478] | Molecular organization in site-specific recombination: the catalytic domain of bacteriophage HP1 integrase at 2.7 A resolution., Hickman AB, Waninger S, Scocca JJ, Dyda F, Cell. 1997 Apr 18;89(2):227-37. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9108478 9108478] | ||
| - | [[Category: | + | [[Category: Haemophilus phage hp1]] |
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Dyda, F.]] | [[Category: Dyda, F.]] | ||
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[[Category: recombination]] | [[Category: recombination]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:33:01 2007'' |
Revision as of 09:28, 30 October 2007
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CATALYTIC DOMAIN OF BACTERIOPHAGE HP1 INTEGRASE
Overview
HP1 integrase promotes site-specific recombination of the HP1 genome into, that of Haemophilus influenzae. The isolated C-terminal domain (residues, 165-337) of the protein interacts with the recombination site and contains, the four catalytic residues conserved in the integrase family. This domain, represents a novel fold consisting principally of well-packed alpha, helices, a surface beta sheet, and an ordered 17-residue C-terminal tail., The conserved triad of basic residues and the active-site tyrosine are, contributed by a single monomer and occupy fixed positions in a defined, active-site cleft. Dimers are formed by mutual interactions of the tail of, one monomer with an adjacent monomer; this orients active-site clefts, antiparallel to each other.
About this Structure
1AIH is a [Single protein] structure of sequence from [Haemophilus phage hp1] with SO4 and MG as [ligands]. Structure known Active Sites: ACA, ACB, ACC and ACD. Full crystallographic information is available from [OCA].
Reference
Molecular organization in site-specific recombination: the catalytic domain of bacteriophage HP1 integrase at 2.7 A resolution., Hickman AB, Waninger S, Scocca JJ, Dyda F, Cell. 1997 Apr 18;89(2):227-37. PMID:9108478
Page seeded by OCA on Tue Oct 30 11:33:01 2007
