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6zri

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Current revision (11:57, 1 February 2024) (edit) (undo)
 
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<StructureSection load='6zri' size='340' side='right'caption='[[6zri]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='6zri' size='340' side='right'caption='[[6zri]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6zri]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZRI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZRI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6zri]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZRI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZRI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DWZ:(2S,3R,4S)-4-{[(3S,5S)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-2-[(1S,2R)-1-FORMYL-2-HYDROXYPROPYL]-3-METHYL-3,4-DIHYDRO-2H-PYRROLE-5-CARBOXYLIC+ACID'>DWZ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DWZ:(2S,3R,4S)-4-{[(3S,5S)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-2-[(1S,2R)-1-FORMYL-2-HYDROXYPROPYL]-3-METHYL-3,4-DIHYDRO-2H-PYRROLE-5-CARBOXYLIC+ACID'>DWZ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6zrg|6zrg]], [[6zrh|6zrh]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaoxa-10, blaOXA-10, oxa-10, BK373_28375, CQP61_30695, E4K55_27185, FORC82_p097, GII67_09965 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zri OCA], [https://pdbe.org/6zri PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zri RCSB], [https://www.ebi.ac.uk/pdbsum/6zri PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zri ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zri OCA], [https://pdbe.org/6zri PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zri RCSB], [https://www.ebi.ac.uk/pdbsum/6zri PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zri ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q7BNC2_ECOLX Q7BNC2_ECOLX]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Benvenuti, M]]
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[[Category: Benvenuti M]]
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[[Category: Docquier, J D]]
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[[Category: De Luca F]]
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[[Category: Luca, F De]]
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[[Category: Di Pisa F]]
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[[Category: Mangani, S]]
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[[Category: Docquier JD]]
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[[Category: Pisa, F Di]]
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[[Category: Mangani S]]
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[[Category: Pozzi, C]]
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[[Category: Pozzi C]]
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[[Category: Tassone, G]]
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[[Category: Tassone G]]
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[[Category: Acylenzyme]]
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[[Category: Carbapenem]]
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[[Category: Hydrolase]]
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[[Category: Laboratory variant]]
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[[Category: Meropenem]]
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[[Category: Oxa-10loop24]]
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Current revision

Crystal structure of OXA-10loop24 in complex with meropenem

PDB ID 6zri

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