3cxm
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='3cxm' size='340' side='right'caption='[[3cxm]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='3cxm' size='340' side='right'caption='[[3cxm]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3cxm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3cxm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_naiffi Leishmania naiffi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CXM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CXM FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene>, <scene name='pdbligand=URB:5-BROMOPYRIMIDINE-2,4(1H,3H)-DIONE'>URB</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene>, <scene name='pdbligand=URB:5-BROMOPYRIMIDINE-2,4(1H,3H)-DIONE'>URB</scene></td></tr> | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cxm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cxm OCA], [https://pdbe.org/3cxm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cxm RCSB], [https://www.ebi.ac.uk/pdbsum/3cxm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cxm ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cxm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cxm OCA], [https://pdbe.org/3cxm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cxm RCSB], [https://www.ebi.ac.uk/pdbsum/3cxm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cxm ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/D0VWU0_9TRYP D0VWU0_9TRYP] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.[HAMAP-Rule:MF_03166][RuleBase:RU003780] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 24: | Line 26: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Leishmania naiffi]] | |
| - | + | [[Category: Larson ET]] | |
| - | + | [[Category: Merritt EA]] | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | [[Category: Leishmania]] | + | |
| - | [[Category: | + | |
| - | [[Category: | + | |
| - | + | ||
Current revision
Leishmania naiffi uracil-DNA glycosylase in complex with 5-bromouracil
| |||||||||||
