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3d9s

From Proteopedia

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Current revision (15:05, 1 November 2023) (edit) (undo)
 
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<StructureSection load='3d9s' size='340' side='right'caption='[[3d9s]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3d9s' size='340' side='right'caption='[[3d9s]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3d9s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D9S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D9S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3d9s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D9S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D9S FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PS6:O-[(S)-{[(2S)-2-(HEXANOYLOXY)-3-(TETRADECANOYLOXY)PROPYL]OXY}(HYDROXY)PHOSPHORYL]-D-SERINE'>PS6</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AQP5 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PS6:O-[(S)-{[(2S)-2-(HEXANOYLOXY)-3-(TETRADECANOYLOXY)PROPYL]OXY}(HYDROXY)PHOSPHORYL]-D-SERINE'>PS6</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d9s OCA], [https://pdbe.org/3d9s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d9s RCSB], [https://www.ebi.ac.uk/pdbsum/3d9s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d9s ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d9s OCA], [https://pdbe.org/3d9s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d9s RCSB], [https://www.ebi.ac.uk/pdbsum/3d9s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d9s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/AQP5_HUMAN AQP5_HUMAN]] Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.
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[https://www.uniprot.org/uniprot/AQP5_HUMAN AQP5_HUMAN] Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Backmark, A]]
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[[Category: Backmark A]]
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[[Category: Fellert, M]]
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[[Category: Fellert M]]
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[[Category: Horsefield, R]]
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[[Category: Horsefield R]]
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[[Category: Johanson, U]]
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[[Category: Johanson U]]
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[[Category: Kjellbom, P]]
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[[Category: Kjellbom P]]
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[[Category: Kvassman, J]]
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[[Category: Kvassman J]]
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[[Category: Neutze, R]]
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[[Category: Neutze R]]
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[[Category: Norden, K]]
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[[Category: Norden K]]
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[[Category: Scheltinga, A C.Terwisscha Van]]
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[[Category: Terwisscha Van Scheltinga AC]]
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[[Category: Tornroth-Horsefield, S]]
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[[Category: Tornroth-Horsefield S]]
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[[Category: Aqp]]
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[[Category: Aquaglyceroporin]]
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[[Category: Aquaporin]]
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[[Category: Ar/r]]
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[[Category: Glycoprotein]]
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[[Category: Lipid]]
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[[Category: Membrane]]
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[[Category: Membrane protein]]
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[[Category: Npa]]
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[[Category: Phosphatidylserine]]
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[[Category: Psf]]
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[[Category: Transmembrane]]
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[[Category: Transport]]
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[[Category: Water channel]]
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[[Category: Water transport]]
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Current revision

Human Aquaporin 5 (AQP5) - High Resolution X-ray Structure

PDB ID 3d9s

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