Pyrroline-5-carboxylate reductase
From Proteopedia
(Difference between revisions)
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**[[2izz]] - hPYCR1 + NAD <br /> | **[[2izz]] - hPYCR1 + NAD <br /> | ||
**[[2gra]], [[5uat]], [[5uaw]], [[5uax]] - hPYCR1 + NADP<br /> | **[[2gra]], [[5uat]], [[5uaw]], [[5uax]] - hPYCR1 + NADP<br /> | ||
| + | **[[8dkg]] – hPYCR1 (mutant) + NAD<br /> | ||
**[[2gr9]] - hPYCR1 + glutamate + NAD<br /> | **[[2gr9]] - hPYCR1 + glutamate + NAD<br /> | ||
**[[5uau]], [[6xp0]] - hPYCR1 + proline derivative<br /> | **[[5uau]], [[6xp0]] - hPYCR1 + proline derivative<br /> | ||
Current revision
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3D structures of pyrroline-5-carboxylate reductase
04-October-2023
References
- ↑ Giberti S, Funck D, Forlani G. Delta1-Pyrroline-5-carboxylate reductase from Arabidopsis thaliana: stimulation or inhibition by chloride ions and feedback regulation by proline depend on whether NADPH or NADH acts as co-substrate. New Phytol. 2014 May;202(3):911-9. doi: 10.1111/nph.12701. Epub 2014 Jan 28. PMID:24467670 doi:http://dx.doi.org/10.1111/nph.12701
- ↑ Nakayama T, Al-Maawali A, El-Quessny M, Rajab A, Khalil S, Stoler JM, Tan WH, Nasir R, Schmitz-Abe K, Hill RS, Partlow JN, Al-Saffar M, Servattalab S, LaCoursiere CM, Tambunan DE, Coulter ME, Elhosary PC, Gorski G, Barkovich AJ, Markianos K, Poduri A, Mochida GH. Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination. Am J Hum Genet. 2015 May 7;96(5):709-19. doi: 10.1016/j.ajhg.2015.03.003. Epub, 2015 Apr 9. PMID:25865492 doi:http://dx.doi.org/10.1016/j.ajhg.2015.03.003
- ↑ Meng Z, Lou Z, Liu Z, Li M, Zhao X, Bartlam M, Rao Z. Crystal structure of human pyrroline-5-carboxylate reductase. J Mol Biol. 2006 Jun 23;359(5):1364-77. Epub 2006 May 11. PMID:16730026 doi:10.1016/j.jmb.2006.04.053

