3dxz

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Current revision (15:15, 1 November 2023) (edit) (undo)
 
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<StructureSection load='3dxz' size='340' side='right'caption='[[3dxz]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
<StructureSection load='3dxz' size='340' side='right'caption='[[3dxz]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3dxz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DXZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DXZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3dxz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DXZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DXZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3dxx|3dxx]], [[3dxy|3dxy]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trmB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/tRNA_(guanine(46)-N(7))-methyltransferase tRNA (guanine(46)-N(7))-methyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.33 2.1.1.33] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dxz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dxz OCA], [https://pdbe.org/3dxz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dxz RCSB], [https://www.ebi.ac.uk/pdbsum/3dxz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dxz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dxz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dxz OCA], [https://pdbe.org/3dxz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dxz RCSB], [https://www.ebi.ac.uk/pdbsum/3dxz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dxz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TRMB_ECOLI TRMB_ECOLI]] Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
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[https://www.uniprot.org/uniprot/TRMB_ECOLI TRMB_ECOLI] Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Gao, Y X]]
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[[Category: Gao YX]]
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[[Category: Liu, Q]]
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[[Category: Liu Q]]
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[[Category: Niu, L W]]
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[[Category: Niu LW]]
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[[Category: Teng, M K]]
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[[Category: Teng MK]]
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[[Category: Zhou, H H]]
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[[Category: Zhou HH]]
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[[Category: Methyltransferase]]
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[[Category: Rossmann fold methyltransferase]]
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[[Category: S-adenosyl-l-methionine]]
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[[Category: Transferase]]
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[[Category: Trna modification]]
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[[Category: Trna processing]]
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Current revision

Crystal structure of EcTrmB in complex with SAH

PDB ID 3dxz

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