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Pyruvate kinase 3D structures

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
 +
 +
*Pyruvate kinase muscle
 +
 +
**[[3bjf]], [[3bjt]], [[1t5a]], [[1zjh]] - hPyK M2 muscle - human<br />
 +
**[[3g2g, [[6b6u]], [[4qg6]], [[4qg8]], [[4qg9]], [[4qgc]], [[4yj5]], **[[4wj8]] - hPyK M2 muscle (mutant) <br />
 +
**[[3srf]], [[3srh]] – hPyK M1 muscle<br />
 +
**[[6wp3]], [[6wp4]], [[6wp5]], [[6wp6]] – hPyK M2 muscle (mutant)<br />
 +
**[[1pkm]], [[1pyk]] – PyK muscle – cat <br />
 +
**[[1f3w]], [[8f5t]] – rPyK muscle – rabbit<br />
 +
**[[1f3x]], [[7r6y]] - rPyK muscle (mutant) <br />
 +
 +
*Pyruvate kinase muscle binary complexes
 +
 +
**[[4b2d]] - hPyK M2 muscle + fructose bisphosphate<br />
 +
**[[4rpp]] - hPyK M2 muscle (mutant) + fructose bisphosphate<br />
 +
**[[4fxj]] - hPyK M2 muscle + phenylalanine<br />
 +
**[[6gg3]] - hPyK M2 muscle + alanine<br />
 +
**[[6gg4]] - hPyK M2 muscle + phenylalanine<br />
 +
**[[6gg5]] - hPyK M2 muscle + tryptophan<br />
 +
**[[6gg6]] - hPyK M2 muscle + serine<br />
 +
**[[6nub]] - hPyK M2 muscle (mutant) + serine<br />
 +
**[[6nu1]] - hPyK M2 muscle + cysteine<br />
 +
**[[6nu5]] - hPyK M2 muscle (mutant) + cysteine<br />
 +
**[[6ttf]], [[6tti]], [[6ttq]] - hPyK M2 muscle + inhibitor – Cryo EM<br />
 +
**[[6tth]] - hPyK M2 muscle + threonine – Cryo EM<br />
 +
**[[6v74]], [[6v75]] - hPyK M2 muscle + asparagine <br />
 +
**[[6v76]] - hPyK M2 muscle + valine <br />
 +
**[[8g2e]] - hPyK muscle + activator <br />
 +
**[[8f5u]] - rPyK muscle + pyruvate <br />
 +
 +
*Pyruvate kinase muscle higher complexes
 +
 +
**[[3me3]] – hPyK M1/M2 muscle + aniline derivative + fructose bisphosphate <br />
 +
**[[4g1n]] - hPyK M1/M2 muscle + pyridazine derivative + oxalate<br />
 +
**[[3h6o]] - hPyK M1/M2 muscle + pyridazine derivative + fructose bisphosphate<br />
 +
**[[3gqy]], [[3gr4]], [[3u2z]] - hPyK M1/M2 muscle + piperazine derivative + fructose bisphosphate<br />
 +
**[[8hmq]], [[8hmr]], [[8hms]], [[8hmu]] - hPyK muscle (mutant) + Pi + fructose bisphosphate<br />
 +
**[[5x0i]] - hPyK M2 muscle (mutant) + serine + fructose bisphosphate<br />
 +
**[[7l21]] - hPyK M2 muscle (mutant) + oxalate + fructose bisphosphate<br />
 +
**[[6jfb]] - hPyK M2 muscle + serine + phosphate<br />
 +
**[[5x1v]], [[5x1w]] - hPyK M2 muscle + activator + fructose bisphosphate<br />
 +
**[[4jpg]] - hPyK M1/M2 muscle + pyrimidine derivative +fructosebisphosphate<br />
 +
**[[3srd]] - hPyK M1/M2 muscle + oxalate + fructose bisphosphate<br />
 +
**[[4fxf]] - hPyK M1/M2 muscle + oxalate + ATP + fructose bisphosphate<br />
 +
**[[3n25]] – rPyK M1/M2 muscle + proline + Mn + pyruvate <br />
 +
**[[2g50 - rPyK M1/M2 muscle + alanine + Mn + pyruvate<br />
 +
**[[8f6m]] - rPyK muscle + Ala + Mn + ADP<br />
 +
**[[1pkn]] - rPyK muscle + Mn + pyruvate<br />
 +
**[[1aqf]] – rPyK muscle + Mg + phospholactate<br />
 +
**[[1a49]], [[1a5u]] - rPyK muscle + ATP + oxalate<br />
 +
 +
*Pyruvate kinase liver
 +
 +
**[[7qdn]] - hPyK liver (mutant)<br />
 +
**[[2vgb]] – hPyK liver<br />)
 +
**[[6nn5]], [[6nn7]], [[6nn8]], 2vgf, 2vgg, 2vgi – hPyK liver (mutant)<br />
 +
**[[6nn4]] - hPyK M2 liver (mutant) + fructose bisphosphate<br />
 +
**[[6ech]], [[6eck]] - PyK liver + fructose bisphosphate - rat<br />
 +
**[[5sc8]], [[5sc9]], [[5sca]], [[5scb]], [[5scc]], [[5scd]], [[5sce]], [[5scf]], [[5scg]], [[5sch]], [[5sci]], [[5scj]], [[5sck]], [[5scl]], [[5sdt]], [[7qzu]] - hPyK liver + anthracene derivative + fructose bisphosphate<br />
 +
**[[7frv]], [[7frw]], [[7frx]], [[7fry]], [[7frz]], [[7fs0]], [[7fs1]], [[7fs2]], [[7fs3]], [[7fs4]], [[7fs5]], [[7fs6]], [[7fs8]], [[7fs9]], [[7fsa]], [[7fsb]], [[7fsc]], [[7fsd]] - hPyK liver + modulator + fructose bisphosphate<br />
 +
**[[4ima]], [[4ip7]] - hPyK liver (mutant) + citrate + adenosine + fructose bisphosphate<br />
 +
*Pyruvate kinase
*Pyruvate kinase
-
**[[3bjf]], [[3bjt]], [[1t5a]], [[1zjh]], [[3srf]], [[3srh]] - hPyK M1/M2 - human<br />
 
-
**[[4wj8]], [[4qg6]], [[4qg8]], [[4qg9]], [[4qgc]], [[3g2g]], [[4yj5]], [[6b6u]] - hPyK M1/M2 (mutant)<br />
 
-
**[[2vgb]] – hPyK LR<br />
 
-
**[[6nn5]], [[6nn7]], [[6nn8]], [[2vgf]], [[2vgg]], [[2vgi]] – hPyK LR (mutant)<br />
 
-
**[[1pkm]], [[1pyk]] – PyK – cat<br />
 
-
**[[1f3w]] – rPyK – rabbit<br />
 
-
**[[1f3x]] - rPyK (mutant) <br />
 
**[[6du6]] – PyK - mosquito<br />
**[[6du6]] – PyK - mosquito<br />
-
**[[1pky]], [[4yng]], [[6k0k]] – EcPyK - ''Eschericia coli''<br />
+
**[[1pky]], [[4yng]], [[6k0k]] – EcPyK - Eschericia coli<br />
-
**[[1e0t]], [[1e0u]] - EcPyK (mutant) <br />
+
**[[1e0t]], [[1e0u]], [[8edq]], [[8edr]], [[8eds]], [[8edt]], [[8eq0]], [[8eq1]], [[8eq3]], [[8eu4]] - EcPyK (mutant) <br />
-
**[[3t05]], [[3t0t]] – SaPyK – ''Staphylococcus aureus''<br />
+
**[[3t05]], [[3t0t]] – SaPyK – Staphylococcus aureus<br />
-
**[[3qtg]] – PyK – ''Pyrobaculum aerophilum''<br />
+
**[[3qtg]] – PyK – Pyrobaculum aerophilum<br />
-
**[[4krz]] - TcPyK – ''Trypanosoma cruzei''<br />
+
**[[4krz]] - TcPyK – Trypanosoma cruzei<br />
-
**[[5wrp]] - MtPyK – ''Mycobacterium tuberculosis''<br />
+
**[[5wrp]] - MtPyK – Mycobacterium tuberculosis<br />
-
**[[3hqn]], [[3e0w]], [[1pkl]] – LmPyK – ''Leishmania mexicana''<br />
+
**[[3hqn]], [[3e0w]], [[1pkl]] – LmPyK – Leishmania mexicana<br />
-
**[[3khd]] – PfPyK – ''Plasmodium falciparum''<br />
+
**[[3khd]], [[7z4m]] – PfPyK – Plasmodium falciparum<br />
-
**[[3gg8]], [[3eoe]] – PyK – ''Toxoplasma gondii''<br />
+
**[[7z4q]], [[7z4r]] - PfPyK (mutant)<br />
-
**[[3ma8]], [[4drs]] – PyK – ''Cryptosporidium parvum''<br />
+
**[[3gg8]], [[3eoe]] – PyK – Toxoplasma gondii<br />
-
**[[2e28]] - PyK (mutant) – ''Geobacillus stearothermophilus''<br />
+
**[[3ma8]], [[4drs]] – CpPyK – Cryptosporidium parvum<br />
-
**[[7oo1]] – PaPyK – ''Pseudomonas aeruginosa''<br />
+
**[[2e28]] - PyK (mutant) – Geobacillus stearothermophilus<br />
 +
**[[7oo1]] – PaPyK – Pseudomonas aeruginosa<br />
 +
**[[7ueh]] – PyK – Zymomonas mobilis<br />
 +
**[[8ias]] - SpPyK – Streptococcus pneumoniae<br />
*Pyruvate kinase binary complex
*Pyruvate kinase binary complex
-
**[[4b2d]] - hPyK M1/M2 + fructose bisphosphate<br />
+
**[[3qv9]] – TcPyK + Ponceau S <br />
-
**[[4rpp]], [[6nn4]] - hPyK M2 (mutant) + fructose bisphosphate<br />
+
-
**[[4fxj]] - hPyK M1/M2 + phenylalanine<br />
+
-
**[[6gg3]] - hPyK M2 + alanine<br />
+
-
**[[6gg4]] - hPyK M2 + phenylalanine<br />
+
-
**[[6gg5]] - hPyK M2 + tryptophan<br />
+
-
**[[6gg6]] - hPyK M2 + serine<br />
+
-
**[[6nub]] - hPyK M2 (mutant) + serine<br />
+
-
**[[6nu1]] - hPyK M2 + cysteine<br />
+
-
**[[6nu5]] - hPyK M2 (mutant) + cysteine<br />
+
-
**[[6ttf]], [[6tti]], [[6ttq]] - hPyK M2 + inhibitor – Cryo EM<br />
+
-
**[[6tth]] - hPyK M2 + threonine – Cryo EM<br />
+
-
**[[6v74]], [[6v75]] - hPyK M2+ asparagine <br />
+
-
**[[6v76]] - hPyK M2 + valine <br />
+
-
**[[6ech]], [[6eck]] - PyK PKLR + fructose bisphosphate - rat<br />
+
-
**[[5x1v]], [[5x1w]] - hPyK M2 + inhibitor<br />
+
-
**[[4rpp]] - hPyK M2 (mutant) + fructose bisphosphate<br />**[[3qv9]] – TcPyK + Ponceau S <br />
+
**[[3qv6]] – LmPyK + acid blue 80<br />
**[[3qv6]] – LmPyK + acid blue 80<br />
-
**[[3e0v]] – LmPyK + sulfate<br />
+
**[[3e0v]] – LmPyK + sulfate <br />
**[[3hqq]] - LmPyK + fructose bisphosphate<br />
**[[3hqq]] - LmPyK + fructose bisphosphate<br />
**[[3qv8]] – LmPyK + benzothiazole<br />
**[[3qv8]] – LmPyK + benzothiazole<br />
Line 53: Line 95:
**[[3is4]], [[3ktx]] – LmPyK + pyrenetetrasulfonic acid<br />
**[[3is4]], [[3ktx]] – LmPyK + pyrenetetrasulfonic acid<br />
**[[3t07]] – SaPyK + bis-indole alkaloid<br />
**[[3t07]] – SaPyK + bis-indole alkaloid<br />
-
**[[4hyw]] – TbPyK + fructose bisphosphate – ''Trypanosoma brucei''<br />
+
**[[4hyw]] – TbPyK + fructose bisphosphate – Trypanosoma brucei<br />
-
**[[6su1]], [[6su2]] – PyK + citrate – ''Trypanosoma congolense''<br />
+
**[[6su1]], [[6su2]] – PyK + citrate – Trypanosoma congolense<br />
**[[5ws8]] - MtPyK + oxalate<br />
**[[5ws8]] - MtPyK + oxalate<br />
**[[6p0y]] - CpPyK + ADP<br />
**[[6p0y]] - CpPyK + ADP<br />
 +
**[[8iav]] - SpPyK + fructose bisphosphate <br />
 +
**[[8iat]] - SpPyK + oxalate<br />
 +
**[[8iaw]] - SpPyK + phosphoenolpyruvate<br />
 +
**[[7z4n]] -PfPyK + pyruvate <br />
-
*Pyruvate kinase higher complex
+
*Pyruvate kinase higher complexes
-
**[[3me3]] – hPyK M1/M2 + aniline derivative + fructose bisphosphate<br />
 
-
**[[4g1n]] - hPyK M1/M2 + pyridazine derivative + oxalate<br />
 
-
**[[3h6o]] - hPyK M1/M2 + pyridazine derivative + fructose bisphosphate<br />
 
-
**[[3gqy]], [[3gr4]], [[3u2z]] - hPyK M1/M2 + piperazine derivative + fructose bisphosphate<br />
 
-
**[[5x0i]] - hPyK M2 (mutant) + serine + fructose bisphosphate<br />
 
-
**[[7l21]] - hPyK M2 (mutant) + oxalate + fructose bisphosphate<br />
 
-
**[[6jfb]] - hPyK M2 + serine + phosphate<br />
 
-
**[[5x1v]], [[5x1w]] - hPyK M2 + activator + fructose bisphosphate<br />
 
-
**[[4jpg]] - hPyK M1/M2 + pyrimidine derivative + fructose bisphosphate<br />
 
-
**[[3srd]] - hPyK M1/M2 + oxalate + fructose bisphosphate<br />
 
-
**[[4fxf]] - hPyK M1/M2 + oxalate + ATP + fructose bisphosphate<br />
 
-
**[[4ima]], [[4ip7]] - hPyK L (mutant) + citrate + adenosine + fructose bisphosphate<br />
 
-
**[[3n25]] – rPyK M1/M2 + proline + Mn + pyruvate<br />
 
-
**[[2g50]] - rPyK M1/M2 + alanine + Mn + pyruvate<br />
 
-
**[[1pkn]] - rPyK + Mn + pyruvate<br />
 
-
**[[1aqf]] – rPyK + Mg + phospholactate<br />
 
-
**[[1a49]], [[1a5u]] - rPyK + ATP + oxalate<br />
 
**[[1a3w]] – yPyK + Mn + phosphoglycolic acid + fructose bisphosphate – yeast<br />
**[[1a3w]] – yPyK + Mn + phosphoglycolic acid + fructose bisphosphate – yeast<br />
**[[1a3x]] - yPyK + Mn + phosphoglycolic acid<br />
**[[1a3x]] - yPyK + Mn + phosphoglycolic acid<br />
Line 93: Line 122:
**[[3qv7]] – LmPyK + acid blue 25 + Ponceau S<br />
**[[3qv7]] – LmPyK + acid blue 25 + Ponceau S<br />
**[[3srk]] – LmPyK + saccharine + inhibitor<br />
**[[3srk]] – LmPyK + saccharine + inhibitor<br />
-
**[[6qxl]] – PaPyK + malonate + glucose-6-phosphate + Mg <br />
+
**[[6qxl]] – PaPyK + malonate + glucose-6-phosphate + Mg<br />
**[[6ksh]] – PfPyK + oxalate + ATP <br />
**[[6ksh]] – PfPyK + oxalate + ATP <br />
 +
**[[8iax]] - SpPyK + fructose bisphosphate + phosphoenolpyruvate<br />
 +
**[[8iau]] - SpPyK + fructose bisphosphate + oxalate<br />
}}
}}
[[Category: Topic Page]]
[[Category: Topic Page]]

Revision as of 08:20, 5 October 2023

3D structures of pyruvate kinase

Updated on 05-October-2023 {{#tree:id=OrganizedByTopic|openlevels=0|

  • Pyruvate kinase muscle
  • Pyruvate kinase muscle binary complexes
    • 4b2d - hPyK M2 muscle + fructose bisphosphate
    • 4rpp - hPyK M2 muscle (mutant) + fructose bisphosphate
    • 4fxj - hPyK M2 muscle + phenylalanine
    • 6gg3 - hPyK M2 muscle + alanine
    • 6gg4 - hPyK M2 muscle + phenylalanine
    • 6gg5 - hPyK M2 muscle + tryptophan
    • 6gg6 - hPyK M2 muscle + serine
    • 6nub - hPyK M2 muscle (mutant) + serine
    • 6nu1 - hPyK M2 muscle + cysteine
    • 6nu5 - hPyK M2 muscle (mutant) + cysteine
    • 6ttf, 6tti, 6ttq - hPyK M2 muscle + inhibitor – Cryo EM
    • 6tth - hPyK M2 muscle + threonine – Cryo EM
    • 6v74, 6v75 - hPyK M2 muscle + asparagine
    • 6v76 - hPyK M2 muscle + valine
    • 8g2e - hPyK muscle + activator
    • 8f5u - rPyK muscle + pyruvate
  • Pyruvate kinase muscle higher complexes
    • 3me3 – hPyK M1/M2 muscle + aniline derivative + fructose bisphosphate
    • 4g1n - hPyK M1/M2 muscle + pyridazine derivative + oxalate
    • 3h6o - hPyK M1/M2 muscle + pyridazine derivative + fructose bisphosphate
    • 3gqy, 3gr4, 3u2z - hPyK M1/M2 muscle + piperazine derivative + fructose bisphosphate
    • 8hmq, 8hmr, 8hms, 8hmu - hPyK muscle (mutant) + Pi + fructose bisphosphate
    • 5x0i - hPyK M2 muscle (mutant) + serine + fructose bisphosphate
    • 7l21 - hPyK M2 muscle (mutant) + oxalate + fructose bisphosphate
    • 6jfb - hPyK M2 muscle + serine + phosphate
    • 5x1v, 5x1w - hPyK M2 muscle + activator + fructose bisphosphate
    • 4jpg - hPyK M1/M2 muscle + pyrimidine derivative +fructosebisphosphate
    • 3srd - hPyK M1/M2 muscle + oxalate + fructose bisphosphate
    • 4fxf - hPyK M1/M2 muscle + oxalate + ATP + fructose bisphosphate
    • 3n25 – rPyK M1/M2 muscle + proline + Mn + pyruvate
    • [[2g50 - rPyK M1/M2 muscle + alanine + Mn + pyruvate
    • 8f6m - rPyK muscle + Ala + Mn + ADP
    • 1pkn - rPyK muscle + Mn + pyruvate
    • 1aqf – rPyK muscle + Mg + phospholactate
    • 1a49, 1a5u - rPyK muscle + ATP + oxalate
  • Pyruvate kinase liver


  • Pyruvate kinase
    • 6du6 – PyK - mosquito
    • 1pky, 4yng, 6k0k – EcPyK - Eschericia coli
    • 1e0t, 1e0u, 8edq, 8edr, 8eds, 8edt, 8eq0, 8eq1, 8eq3, 8eu4 - EcPyK (mutant)
    • 3t05, 3t0t – SaPyK – Staphylococcus aureus
    • 3qtg – PyK – Pyrobaculum aerophilum
    • 4krz - TcPyK – Trypanosoma cruzei
    • 5wrp - MtPyK – Mycobacterium tuberculosis
    • 3hqn, 3e0w, 1pkl – LmPyK – Leishmania mexicana
    • 3khd, 7z4m – PfPyK – Plasmodium falciparum
    • 7z4q, 7z4r - PfPyK (mutant)
    • 3gg8, 3eoe – PyK – Toxoplasma gondii
    • 3ma8, 4drs – CpPyK – Cryptosporidium parvum
    • 2e28 - PyK (mutant) – Geobacillus stearothermophilus
    • 7oo1 – PaPyK – Pseudomonas aeruginosa
    • 7ueh – PyK – Zymomonas mobilis
    • 8ias - SpPyK – Streptococcus pneumoniae
  • Pyruvate kinase binary complex
    • 3qv9 – TcPyK + Ponceau S
    • 3qv6 – LmPyK + acid blue 80
    • 3e0v – LmPyK + sulfate
    • 3hqq - LmPyK + fructose bisphosphate
    • 3qv8 – LmPyK + benzothiazole
    • 3pp7 – LmPyK + suramin
    • 3is4, 3ktx – LmPyK + pyrenetetrasulfonic acid
    • 3t07 – SaPyK + bis-indole alkaloid
    • 4hyw – TbPyK + fructose bisphosphate – Trypanosoma brucei
    • 6su1, 6su2 – PyK + citrate – Trypanosoma congolense
    • 5ws8 - MtPyK + oxalate
    • 6p0y - CpPyK + ADP
    • 8iav - SpPyK + fructose bisphosphate
    • 8iat - SpPyK + oxalate
    • 8iaw - SpPyK + phosphoenolpyruvate
    • 7z4n -PfPyK + pyruvate
  • Pyruvate kinase higher complexes
    • 1a3w – yPyK + Mn + phosphoglycolic acid + fructose bisphosphate – yeast
    • 1a3x - yPyK + Mn + phosphoglycolic acid
    • 4hyv – TbPyK + phosphoenolpyruvate + fructose bisphosphate
    • 4kct – TbPyK + pyruvate + fructose bisphosphate
    • 4kcu – TbPyK + malate + fructose bisphosphate
    • 4kcv – TbPyK + oxoglutarate + fructose bisphosphate
    • 4kcw – TbPyK + oxalate + fructose bisphosphate
    • 4ks0 – TcPyK + oxalate + fructose bisphosphate
    • 5ws9 – MtPyK + oxalate + AMP + ATP
    • 5wsa – MtPyK + oxalate + glucose-6-phosphate
    • 5wsb, 5wsc – MtPyK + oxalate + glucose-6-phosphate + AMP
    • 6ito – MtPyK + oxalate + ribose-5-phosphate + AMP
    • 3hqo – LmPyK + ATP + oxalate
    • 3hqp - LmPyK + ATP + oxalate + fructose bisphosphate
    • 3qv7 – LmPyK + acid blue 25 + Ponceau S
    • 3srk – LmPyK + saccharine + inhibitor
    • 6qxl – PaPyK + malonate + glucose-6-phosphate + Mg
    • 6ksh – PfPyK + oxalate + ATP
    • 8iax - SpPyK + fructose bisphosphate + phosphoenolpyruvate
    • 8iau - SpPyK + fructose bisphosphate + oxalate

}}

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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