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| - | + | =''Metabotropic Glutamate Receptor''= | |
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| - | == | + | <StructureSection load='7epa' size='340' side='right' caption='Inactive Metabotropic Glutamate Receptor 2 PDB:[http://www.rcsb.org/pdb/explore/explore.do?structureId=7epa 7epa]' scene='90/905627/Inactive_mglu2_first_picture/1'> |
| - | + | [[Image:Inactive mGlu.png|400 px|right|thumb|Figure 1. The coolest image of this protein EVAH!!!]] | |
| + | [https://en.wikipedia.org/wiki/Metabotropic_glutamate_receptor Metabotropic glutamate receptor] | ||
| - | == Relevance == | ||
| - | = | + | <ref name="Ransey">PMID:28504306</ref> |
| - | + | <ref name="Seven">PMID:34194039</ref> | |
| + | |||
| + | == Introduction == | ||
| + | <scene name='90/905627/Inactive_mglu2/1'>Inactive mGlu2</scene> | ||
| + | === Relevance === | ||
| + | |||
| + | === Function === | ||
| + | |||
| + | <ref name="Ransey" /> | ||
| + | |||
| + | |||
| + | <ref name="Seven" /> | ||
| + | |||
| + | == Structure == | ||
| + | |||
| + | === Chains === | ||
| + | <scene name='90/905627/Inactive_mglu2/8'>mGlu2 chains</scene> | ||
| + | ==== Domains ==== | ||
| + | <scene name='90/905627/Mglu2_domains/9'>mGlu2 domains</scene> | ||
| + | |||
| + | === Conformational Changes === | ||
| + | |||
| + | == Clinical Relevance == | ||
| + | |||
| + | === Role === | ||
| + | |||
| + | === Disease === | ||
| + | <scene name='90/905627/Mglu_vft/1'>mGlu VFT</scene> | ||
</StructureSection> | </StructureSection> | ||
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== References == | == References == | ||
<references/> | <references/> | ||
| + | |||
| + | == Student Contributors == | ||
| + | *Courtney Vennekotter | ||
| + | *Cade Chezem | ||
Revision as of 17:18, 25 March 2022
Metabotropic Glutamate Receptor
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References
- ↑ 1.0 1.1 Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
- ↑ 2.0 2.1 Seven AB, Barros-Alvarez X, de Lapeyriere M, Papasergi-Scott MM, Robertson MJ, Zhang C, Nwokonko RM, Gao Y, Meyerowitz JG, Rocher JP, Schelshorn D, Kobilka BK, Mathiesen JM, Skiniotis G. G-protein activation by a metabotropic glutamate receptor. Nature. 2021 Jun 30. pii: 10.1038/s41586-021-03680-3. doi:, 10.1038/s41586-021-03680-3. PMID:34194039 doi:http://dx.doi.org/10.1038/s41586-021-03680-3
Student Contributors
- Courtney Vennekotter
- Cade Chezem
