7tx2
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human phenylethanolamine N-methyltransferase (PNMT) in complex with (2S)-2-amino-4-(((5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(4-(7,8-dichloro-1,2,3,4-tetrahydroisoquinolin-4-yl)butyl)amino)butanoic acid== | |
| - | + | <StructureSection load='7tx2' size='340' side='right'caption='[[7tx2]], [[Resolution|resolution]] 2.43Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7tx2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TX2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=KNX:5-([(3S)-3-amino-3-carboxypropyl]{4-[(4R)-7,8-dichloro-1,2,3,4-tetrahydroisoquinolin-4-yl]butyl}amino)-5-deoxyadenosine'>KNX</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tx2 OCA], [https://pdbe.org/7tx2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tx2 RCSB], [https://www.ebi.ac.uk/pdbsum/7tx2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tx2 ProSAT]</span></td></tr> |
| - | [[Category: Almo | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Harijan | + | [https://www.uniprot.org/uniprot/PNMT_HUMAN PNMT_HUMAN] Converts noradrenaline to adrenaline. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Almo SC]] | ||
| + | [[Category: Bonanno JB]] | ||
| + | [[Category: Harijan RK]] | ||
| + | [[Category: Mahmoodi N]] | ||
| + | [[Category: Minnow YVT]] | ||
| + | [[Category: Schramm VL]] | ||
Revision as of 10:21, 15 February 2023
Crystal structure of human phenylethanolamine N-methyltransferase (PNMT) in complex with (2S)-2-amino-4-(((5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(4-(7,8-dichloro-1,2,3,4-tetrahydroisoquinolin-4-yl)butyl)amino)butanoic acid
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