1gd7

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1gd7.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1gd7.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1gd7| PDB=1gd7 | SCENE= }}
{{STRUCTURE_1gd7| PDB=1gd7 | SCENE= }}
-
'''CRYSTAL STRUCTURE OF A BIFUNCTIONAL PROTEIN (CSAA) WITH EXPORT-RELATED CHAPERONE AND TRNA-BINDING ACTIVITIES.'''
+
===CRYSTAL STRUCTURE OF A BIFUNCTIONAL PROTEIN (CSAA) WITH EXPORT-RELATED CHAPERONE AND TRNA-BINDING ACTIVITIES.===
-
==Overview==
+
<!--
-
The CsaA protein was first characterized in Bacillus subtilis as a molecular chaperone with export-related activities. Here we report the 2.0 Angstrom-resolution crystal structure of the Thermus thermophilus CsaA protein, designated ttCsaA. Atomic structure and experiments in solution revealed a homodimer as the functional unit. The structure of the ttCsaA monomer is reminiscent of the well known oligonucleotide-binding fold, with the addition of extensions at the N- and C-termini that form an extensive dimer interface. The two identical, large, hydrophobic cavities on the protein surface are likely to constitute the substrate binding sites. The CsaA proteins share essential sequence similarity with the tRNA-binding protein Trbp111. Structure-based sequence analysis suggests a close structural resemblance between these proteins, which may extend to the architecture of the binding sites at the atomic level. These results raise the intriguing possibility that CsaA proteins possess a second, tRNA-binding activity in addition to their export-related function.
+
The line below this paragraph, {{ABSTRACT_PUBMED_11157762}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 11157762 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_11157762}}
==About this Structure==
==About this Structure==
Line 37: Line 41:
[[Category: Rsgi]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 17:26:15 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 05:07:27 2008''

Revision as of 02:07, 1 July 2008

Image:1gd7.png

Template:STRUCTURE 1gd7

CRYSTAL STRUCTURE OF A BIFUNCTIONAL PROTEIN (CSAA) WITH EXPORT-RELATED CHAPERONE AND TRNA-BINDING ACTIVITIES.

Template:ABSTRACT PUBMED 11157762

About this Structure

1GD7 is a Single protein structure of sequence from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

The crystal structure of the ttCsaA protein: an export-related chaperone from Thermus thermophilus., Kawaguchi S, Muller J, Linde D, Kuramitsu S, Shibata T, Inoue Y, Vassylyev DG, Yokoyama S, EMBO J. 2001 Feb 1;20(3):562-9. PMID:11157762

Page seeded by OCA on Tue Jul 1 05:07:27 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1gd7"
Personal tools