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7rrl
From Proteopedia
(Difference between revisions)
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==Alternate Crystal Form of Human Malate Dehydrogenase I== | ==Alternate Crystal Form of Human Malate Dehydrogenase I== | ||
| - | <StructureSection load='7rrl' size='340' side='right'caption='[[7rrl]]' scene=''> | + | <StructureSection load='7rrl' size='340' side='right'caption='[[7rrl]], [[Resolution|resolution]] 2.05Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RRL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RRL FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7rrl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RRL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RRL FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rrl OCA], [https://pdbe.org/7rrl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rrl RCSB], [https://www.ebi.ac.uk/pdbsum/7rrl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rrl ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rrl OCA], [https://pdbe.org/7rrl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rrl RCSB], [https://www.ebi.ac.uk/pdbsum/7rrl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rrl ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/MDHC_HUMAN MDHC_HUMAN] The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MDHC_HUMAN MDHC_HUMAN] Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH (PubMed:3052244). Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation (PubMed:31538237).<ref>PMID:3052244</ref> <ref>PMID:31538237</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Finzel BC]] | [[Category: Finzel BC]] | ||
[[Category: McCue W]] | [[Category: McCue W]] | ||
Current revision
Alternate Crystal Form of Human Malate Dehydrogenase I
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