2m2a

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==NMR solution structure of the two domain PPIase SlpA from Escherichia coli==
==NMR solution structure of the two domain PPIase SlpA from Escherichia coli==
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<StructureSection load='2m2a' size='340' side='right'caption='[[2m2a]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='2m2a' size='340' side='right'caption='[[2m2a]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2m2a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M2A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2m2a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M2A FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m2a OCA], [https://pdbe.org/2m2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m2a RCSB], [https://www.ebi.ac.uk/pdbsum/2m2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m2a ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m2a OCA], [https://pdbe.org/2m2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m2a RCSB], [https://www.ebi.ac.uk/pdbsum/2m2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m2a ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/FKBX_ECOLI FKBX_ECOLI]] PPIases accelerate the folding of proteins. Substrate specificity investigated with 'Suc-Ala-Xaa-Pro-Phe-4-nitroanilide' where Xaa is the amino acid tested, was found to be Phe > Leu >> Ile > Lys = Ala > Trp > His >> Gln.
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[https://www.uniprot.org/uniprot/FKBX_ECOLI FKBX_ECOLI] PPIases accelerate the folding of proteins. Substrate specificity investigated with 'Suc-Ala-Xaa-Pro-Phe-4-nitroanilide' where Xaa is the amino acid tested, was found to be Phe > Leu >> Ile > Lys = Ala > Trp > His >> Gln.
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Balbach J]]
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[[Category: Balbach, J]]
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[[Category: Kovermann M]]
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[[Category: Kovermann, M]]
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[[Category: Weininger U]]
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[[Category: Weininger, U]]
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[[Category: Fkbp fold]]
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[[Category: Isomerase]]
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Revision as of 09:25, 14 June 2023

NMR solution structure of the two domain PPIase SlpA from Escherichia coli

PDB ID 2m2a

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