7lqp
From Proteopedia
(Difference between revisions)
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==Rapid development of potent inhibitors of the HIV integrase-LEDGF interaction by fragment-linking using off-rate screening== | ==Rapid development of potent inhibitors of the HIV integrase-LEDGF interaction by fragment-linking using off-rate screening== | ||
| - | <StructureSection load='7lqp' size='340' side='right'caption='[[7lqp]]' scene=''> | + | <StructureSection load='7lqp' size='340' side='right'caption='[[7lqp]], [[Resolution|resolution]] 2.07Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LQP FirstGlance]. <br> | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LQP FirstGlance]. <br> | ||
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lqp OCA], [https://pdbe.org/7lqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lqp RCSB], [https://www.ebi.ac.uk/pdbsum/7lqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lqp ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YAV:2-[2-[2-[3-[2-[2-[2-[[3-[2-[3-(2-hydroxy-2-oxoethyl)-5-methyl-1-benzofuran-2-yl]ethynyl]phenyl]carbonylamino]ethoxy]ethoxy]ethylcarbamoyl]phenyl]ethynyl]-5-methyl-1-benzofuran-3-yl]ethanoic+acid'>YAV</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lqp OCA], [https://pdbe.org/7lqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lqp RCSB], [https://www.ebi.ac.uk/pdbsum/7lqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lqp ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
Rapid development of potent inhibitors of the HIV integrase-LEDGF interaction by fragment-linking using off-rate screening
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