1l7b

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Current revision (08:07, 3 April 2024) (edit) (undo)
 
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==Solution NMR Structure of BRCT Domain of T. Thermophilus: Northeast Structural Genomics Consortium Target WR64TT==
==Solution NMR Structure of BRCT Domain of T. Thermophilus: Northeast Structural Genomics Consortium Target WR64TT==
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<StructureSection load='1l7b' size='340' side='right'caption='[[1l7b]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='1l7b' size='340' side='right'caption='[[1l7b]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1l7b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L7B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1l7b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L7B FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DNLJ ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 "Flavobacterium thermophilum" Yoshida and Oshima 1971])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA_ligase_(NAD(+)) DNA ligase (NAD(+))], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.2 6.5.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l7b OCA], [https://pdbe.org/1l7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l7b RCSB], [https://www.ebi.ac.uk/pdbsum/1l7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l7b ProSAT], [https://www.topsan.org/Proteins/NESGC/1l7b TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l7b OCA], [https://pdbe.org/1l7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l7b RCSB], [https://www.ebi.ac.uk/pdbsum/1l7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l7b ProSAT], [https://www.topsan.org/Proteins/NESGC/1l7b TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DNLJ_THET8 DNLJ_THET8]] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
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[https://www.uniprot.org/uniprot/DNLJ_THET8 DNLJ_THET8] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Anderson, S]]
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[[Category: Thermus thermophilus]]
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[[Category: Aramini, J]]
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[[Category: Anderson S]]
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[[Category: Bhattacharya, D]]
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[[Category: Aramini J]]
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[[Category: Dixon, B L]]
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[[Category: Bhattacharya D]]
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[[Category: Huang, Y P]]
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[[Category: Dixon BL]]
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[[Category: Monleon, D]]
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[[Category: Huang YP]]
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[[Category: Montelione, G T]]
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[[Category: Monleon D]]
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[[Category: Structural genomic]]
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[[Category: Montelione GT]]
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[[Category: Sahota, G]]
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[[Category: Sahota G]]
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[[Category: Swapna, G V.T]]
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[[Category: Swapna GVT]]
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[[Category: Tejero, R]]
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[[Category: Tejero R]]
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[[Category: Xiao, R]]
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[[Category: Xiao R]]
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[[Category: Yin, C]]
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[[Category: Yin C]]
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[[Category: Autostructure]]
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[[Category: Brct]]
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[[Category: Dna ligase]]
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[[Category: Ligase]]
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[[Category: Nesg]]
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[[Category: PSI, Protein structure initiative]]
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Current revision

Solution NMR Structure of BRCT Domain of T. Thermophilus: Northeast Structural Genomics Consortium Target WR64TT

PDB ID 1l7b

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