User:Kaylin M. Todor/Sandbox1

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=Anaplastic Lymphoma Kinase=
=Anaplastic Lymphoma Kinase=
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<StructureSection load='7lrz' size='350' frame='true' side='right' caption='Structure of the Human ALK GRD' scene=’’>
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<StructureSection load='7lrz' size='350' frame='true' side='right' caption='Structure of the Human ALK GRD' scene=’7lrz_specified_region’>
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<scene name='90/905584/7lrz_specified_region/1'>7LRZ Specified Region</scene>
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<ref name="Li">PMID:34819665</ref>
== Introduction ==
== Introduction ==
==Structure==
==Structure==
[[Image:Specific Interactions Picture.png|400 px|right|thumb|Figure 1. The coolest image of this protein EVAH!!!]]
[[Image:Specific Interactions Picture.png|400 px|right|thumb|Figure 1. The coolest image of this protein EVAH!!!]]
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<ref name="Ransey" />
==Function==
==Function==
==Disease==
==Disease==
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<ref name="Ransey">PMID:28504306</ref>
[https://www.uptodate.com/contents/anaplastic-lymphoma-kinase-alk-fusion-oncogene-positive-non-small-cell-lung-cancer#:~:text=INTRODUCTION%20Anaplastic%20lymphoma%20kinase%20(ALK,of%20NSCLC%20tumors%20%5B1%5D. ALK-positive Lung Cancer]
[https://www.uptodate.com/contents/anaplastic-lymphoma-kinase-alk-fusion-oncogene-positive-non-small-cell-lung-cancer#:~:text=INTRODUCTION%20Anaplastic%20lymphoma%20kinase%20(ALK,of%20NSCLC%20tumors%20%5B1%5D. ALK-positive Lung Cancer]
</StructureSection>
</StructureSection>

Current revision

Anaplastic Lymphoma Kinase

Structure of the Human ALK GRD

Drag the structure with the mouse to rotate

References

  1. Li T, Stayrook SE, Tsutsui Y, Zhang J, Wang Y, Li H, Proffitt A, Krimmer SG, Ahmed M, Belliveau O, Walker IX, Mudumbi KC, Suzuki Y, Lax I, Alvarado D, Lemmon MA, Schlessinger J, Klein DE. Structural basis for ligand reception by anaplastic lymphoma kinase. Nature. 2021 Dec;600(7887):148-152. doi: 10.1038/s41586-021-04141-7. Epub 2021, Nov 24. PMID:34819665 doi:http://dx.doi.org/10.1038/s41586-021-04141-7
  2. 2.0 2.1 Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677

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  • Kaylin Todor

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Kaylin M. Todor

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