7w4a
From Proteopedia
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| - | ==== | + | ==Cryo-EM structure of the gastric proton pump complexed with revaprazan== |
| - | <StructureSection load='7w4a' size='340' side='right'caption='[[7w4a]]' scene=''> | + | <StructureSection load='7w4a' size='340' side='right'caption='[[7w4a]], [[Resolution|resolution]] 2.76Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7w4a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7W4A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7W4A FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w4a OCA], [https://pdbe.org/7w4a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w4a RCSB], [https://www.ebi.ac.uk/pdbsum/7w4a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w4a ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8CK:N-(4-fluorophenyl)-4,5-dimethyl-6-[(1R)-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl]pyrimidin-2-amine'>8CK</scene>, <scene name='pdbligand=BFD:ASPARTATE+BERYLLIUM+TRIFLUORIDE'>BFD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PCW:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PCW</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w4a OCA], [https://pdbe.org/7w4a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w4a RCSB], [https://www.ebi.ac.uk/pdbsum/7w4a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w4a ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/ATP4A_PIG ATP4A_PIG]] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Sus scrofa]] |
| + | [[Category: Abe K]] | ||
| + | [[Category: Morita M]] | ||
| + | [[Category: Tanaka S]] | ||
| + | [[Category: Yamagishi T]] | ||
Revision as of 05:33, 8 September 2022
Cryo-EM structure of the gastric proton pump complexed with revaprazan
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Categories: Large Structures | Sus scrofa | Abe K | Morita M | Tanaka S | Yamagishi T
