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7s23

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Current revision (16:42, 18 October 2023) (edit) (undo)
 
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<StructureSection load='7s23' size='340' side='right'caption='[[7s23]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
<StructureSection load='7s23' size='340' side='right'caption='[[7s23]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7s23]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7S23 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7S23 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7s23]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7S23 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7S23 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.49&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7s23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7s23 OCA], [https://pdbe.org/7s23 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7s23 RCSB], [https://www.ebi.ac.uk/pdbsum/7s23 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7s23 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7s23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7s23 OCA], [https://pdbe.org/7s23 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7s23 RCSB], [https://www.ebi.ac.uk/pdbsum/7s23 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7s23 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/COPA_SCHPO COPA_SCHPO]] The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
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[https://www.uniprot.org/uniprot/COPA_SCHPO COPA_SCHPO] The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Dey, D]]
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[[Category: Schizosaccharomyces pombe]]
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[[Category: Gakhar, L]]
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[[Category: Dey D]]
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[[Category: Hasan, S S]]
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[[Category: Gakhar L]]
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[[Category: Khan, S]]
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[[Category: Hasan SS]]
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[[Category: Martin, M]]
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[[Category: Khan S]]
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[[Category: Pierce, B]]
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[[Category: Martin M]]
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[[Category: Schnicker, N]]
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[[Category: Pierce B]]
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[[Category: Singh, S]]
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[[Category: Schnicker N]]
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[[Category: Coatomer subunit alpha wd40 domain]]
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[[Category: Singh S]]
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[[Category: Protein transport]]
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Current revision

Crystal structure of alpha-COP-WD40 domain, Y139A mutant

PDB ID 7s23

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