2o4v

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Current revision (00:14, 28 December 2023) (edit) (undo)
 
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<StructureSection load='2o4v' size='340' side='right'caption='[[2o4v]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
<StructureSection load='2o4v' size='340' side='right'caption='[[2o4v]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2o4v]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O4V FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2o4v]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O4V FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4v OCA], [https://pdbe.org/2o4v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o4v RCSB], [https://www.ebi.ac.uk/pdbsum/2o4v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o4v ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4v OCA], [https://pdbe.org/2o4v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o4v RCSB], [https://www.ebi.ac.uk/pdbsum/2o4v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o4v ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PORP_PSEAE PORP_PSEAE]] Anion specific, the binding site has higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates (tripolyphosphate and pyrophosphate) while porin P has a higher affinity for orthophosphate.
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[https://www.uniprot.org/uniprot/PORP_PSEAE PORP_PSEAE] Anion specific, the binding site has higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates (tripolyphosphate and pyrophosphate) while porin P has a higher affinity for orthophosphate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pseudomonas aeruginosa pao1]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Bains, M]]
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[[Category: Bains M]]
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[[Category: Hancock, R E]]
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[[Category: Hancock RE]]
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[[Category: Moraes, T F]]
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[[Category: Moraes TF]]
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[[Category: Strynadka, N C]]
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[[Category: Strynadka NC]]
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[[Category: Channel]]
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[[Category: Membrane protein]]
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[[Category: Outer membrane]]
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[[Category: Phosphate]]
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[[Category: Porin]]
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[[Category: Transport]]
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Current revision

An arginine ladder in OprP mediates phosphate specific transfer across the outer membrane

PDB ID 2o4v

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