7r24
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of rat Arc CTD in complex with two anti-Arc nanobodies== | |
| - | + | <StructureSection load='7r24' size='340' side='right'caption='[[7r24]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7r24]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Vicugna_pacos Vicugna pacos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7R24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7R24 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r24 OCA], [https://pdbe.org/7r24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r24 RCSB], [https://www.ebi.ac.uk/pdbsum/7r24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r24 ProSAT]</span></td></tr> |
| - | [[Category: Kursula | + | </table> |
| - | [[Category: Markusson | + | == Function == |
| + | [https://www.uniprot.org/uniprot/ARC_RAT ARC_RAT] Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration (By similarity). Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.<ref>PMID:17088212</ref> <ref>PMID:17088213</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Vicugna pacos]] | ||
| + | [[Category: Kursula P]] | ||
| + | [[Category: Markusson S]] | ||
Current revision
Crystal structure of rat Arc CTD in complex with two anti-Arc nanobodies
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