2pd4
From Proteopedia
(Difference between revisions)
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<StructureSection load='2pd4' size='340' side='right'caption='[[2pd4]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='2pd4' size='340' side='right'caption='[[2pd4]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2pd4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2pd4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1jw7 1jw7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PD4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PD4 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DCN:DICLOSAN'>DCN</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pd4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pd4 OCA], [https://pdbe.org/2pd4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pd4 RCSB], [https://www.ebi.ac.uk/pdbsum/2pd4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pd4 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pd4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pd4 OCA], [https://pdbe.org/2pd4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pd4 RCSB], [https://www.ebi.ac.uk/pdbsum/2pd4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pd4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/FABI_HELPY FABI_HELPY] Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Atcc 43504]] | ||
| - | [[Category: Large Structures]] | ||
| - | [[Category: Lee, H H]] | ||
| - | [[Category: Moon, J H]] | ||
| - | [[Category: Suh, S W]] | ||
| - | [[Category: Antibacterial target]] | ||
| - | [[Category: Enoyl-acp-reductase]] | ||
| - | [[Category: Fabi]] | ||
[[Category: Helicobacter pylori]] | [[Category: Helicobacter pylori]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Lee HH]] |
| + | [[Category: Moon JH]] | ||
| + | [[Category: Suh SW]] | ||
Current revision
Crystal Structure of the Helicobacter pylori Enoyl-Acyl Carrier Protein Reductase in Complex with Hydroxydiphenyl Ether Compounds, Triclosan and Diclosan
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