3gc2

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Current revision (09:11, 30 October 2024) (edit) (undo)
 
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<StructureSection load='3gc2' size='340' side='right'caption='[[3gc2]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='3gc2' size='340' side='right'caption='[[3gc2]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3gc2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GC2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3gc2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GC2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/o-succinylbenzoate_synthase o-succinylbenzoate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.113 4.2.1.113] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gc2 OCA], [https://pdbe.org/3gc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gc2 RCSB], [https://www.ebi.ac.uk/pdbsum/3gc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gc2 ProSAT], [https://www.topsan.org/Proteins/CSGID/3gc2 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gc2 OCA], [https://pdbe.org/3gc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gc2 RCSB], [https://www.ebi.ac.uk/pdbsum/3gc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gc2 ProSAT], [https://www.topsan.org/Proteins/CSGID/3gc2 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MENC_SALTY MENC_SALTY]] Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).[HAMAP-Rule:MF_00470]
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[https://www.uniprot.org/uniprot/MENC_SALTY MENC_SALTY] Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).[HAMAP-Rule:MF_00470]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gc/3gc2_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gc/3gc2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: O-succinylbenzoate synthase]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Anderson, W F]]
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[[Category: Anderson WF]]
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[[Category: Structural genomic]]
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[[Category: Minasov G]]
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[[Category: Minasov, G]]
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[[Category: Onopriyenko O]]
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[[Category: Onopriyenko, O]]
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[[Category: Peterson SN]]
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[[Category: Peterson, S N]]
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[[Category: Savchenko A]]
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[[Category: Savchenko, A]]
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[[Category: Skarina T]]
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[[Category: Skarina, T]]
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[[Category: Wawrzak Z]]
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[[Category: Wawrzak, Z]]
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[[Category: Csgid]]
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[[Category: Idp00994]]
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[[Category: Lyase]]
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[[Category: Magnesium]]
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[[Category: Menaquinone biosynthesis]]
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[[Category: Metal-binding]]
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[[Category: Succinic acid]]
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Current revision

1.85 Angstrom Crystal Structure of O-succinylbenzoate Synthase from Salmonella typhimurium in Complex with Succinic Acid

PDB ID 3gc2

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