3ge1

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Current revision (07:04, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3ge1' size='340' side='right'caption='[[3ge1]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='3ge1' size='340' side='right'caption='[[3ge1]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ge1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staac Staac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GE1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ge1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GE1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3g25|3g25]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">glpK, SACOL1320 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glycerol_kinase Glycerol kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.30 2.7.1.30] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ge1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ge1 OCA], [https://pdbe.org/3ge1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ge1 RCSB], [https://www.ebi.ac.uk/pdbsum/3ge1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ge1 ProSAT], [https://www.topsan.org/Proteins/CSGID/3ge1 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ge1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ge1 OCA], [https://pdbe.org/3ge1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ge1 RCSB], [https://www.ebi.ac.uk/pdbsum/3ge1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ge1 ProSAT], [https://www.topsan.org/Proteins/CSGID/3ge1 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/GLPK_STAAC GLPK_STAAC]] Key enzsyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate (By similarity).[HAMAP-Rule:MF_00186]
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[https://www.uniprot.org/uniprot/GLPK_STAAC GLPK_STAAC] Key enzsyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate (By similarity).[HAMAP-Rule:MF_00186]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Glycerol kinase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Staac]]
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[[Category: Staphylococcus aureus subsp. aureus COL]]
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[[Category: Anderson, W F]]
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[[Category: Anderson WF]]
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[[Category: Brunzelle, J]]
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[[Category: Brunzelle J]]
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[[Category: Structural genomic]]
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[[Category: Minasov G]]
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[[Category: Minasov, G]]
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[[Category: Onopriyenko O]]
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[[Category: Onopriyenko, O]]
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[[Category: Peterson SN]]
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[[Category: Peterson, S N]]
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[[Category: Savchenko A]]
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[[Category: Savchenko, A]]
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[[Category: Skarina T]]
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[[Category: Skarina, T]]
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[[Category: Adp]]
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[[Category: Atp-binding]]
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[[Category: Csgid]]
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[[Category: Glycerol]]
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[[Category: Glycerol metabolism]]
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[[Category: Idp00743]]
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[[Category: Kinase]]
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[[Category: Nucleotide-binding]]
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[[Category: Transferase]]
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Current revision

2.7 Angstrom Crystal Structure of Glycerol Kinase (glpK) from Staphylococcus aureus in Complex with ADP and Glycerol

PDB ID 3ge1

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