Serine hydroxymethyltransferase 3D structures
From Proteopedia
(Difference between revisions)
| Line 8: | Line 8: | ||
**[[6dk3]] – hSHMT 2 – human<br /> | **[[6dk3]] – hSHMT 2 – human<br /> | ||
**[[5x3v]] – hSHMT 2 (mutant)<br /> | **[[5x3v]] – hSHMT 2 (mutant)<br /> | ||
| + | **[[7pzz]] – AtSHMT 2 – ''Arabidopsis thaliana''<br /> | ||
| + | **[[7q00]] – AtSHMT 4<br /> | ||
| + | **[[7qpe]] – AtSHMT 6 <br /> | ||
| + | **[[7qx8]] – AtSHMT 7<br /> | ||
**[[3gbx]] – SHMT – ''Salmonella typhimurium'' <br /> | **[[3gbx]] – SHMT – ''Salmonella typhimurium'' <br /> | ||
**[[3n0l]] – SHMT – ''Campylobacter jejuni''<br /> | **[[3n0l]] – SHMT – ''Campylobacter jejuni''<br /> | ||
| Line 20: | Line 24: | ||
**[[5vmb]] – SHMT – ''Acinetobacter baumannii'' <br /> | **[[5vmb]] – SHMT – ''Acinetobacter baumannii'' <br /> | ||
**[[5z0y]] – SHMT – ''Pichia pastoris'' <br /> | **[[5z0y]] – SHMT – ''Pichia pastoris'' <br /> | ||
| + | **[[7qcw]] – SHMT – ''Pseudomonas chlororaphis'' <br / | ||
*SHMT + PLP | *SHMT + PLP | ||
| Line 25: | Line 30: | ||
**[[1bj4]] - hSHMT 1 + PLP <br /> | **[[1bj4]] - hSHMT 1 + PLP <br /> | ||
**[[6fl5]] – hSHMT 1 (mutant) + PLP<br /> | **[[6fl5]] – hSHMT 1 (mutant) + PLP<br /> | ||
| - | **[[4pvf]] – hSHMT 2 + PLP derivative <br /> | + | **[[4pvf]], [[8aql]], [[8qi7]], [[8ssj]] – hSHMT 2 + PLP derivative <br /> |
**[[1cj0]], [[1rv4]], [[1rvu]] – rSHMT 1 (mutant) + PLP – rabbit <br /> | **[[1cj0]], [[1rv4]], [[1rvu]] – rSHMT 1 (mutant) + PLP – rabbit <br /> | ||
**[[1eji]] – SHMT + PLP derivative – mouse<br /> | **[[1eji]] – SHMT + PLP derivative – mouse<br /> | ||
**[[6uxh]], [[6uxi]], [[6uxk]] , [[6uxl]]– sbSHMT 8 + PLP derivative – soybean<br /> | **[[6uxh]], [[6uxi]], [[6uxk]] , [[6uxl]]– sbSHMT 8 + PLP derivative – soybean<br /> | ||
**[[6cd0]], [[6cd1]] – bmSHMT 3 + PLP derivatives - barrel medic<br /> | **[[6cd0]], [[6cd1]] – bmSHMT 3 + PLP derivatives - barrel medic<br /> | ||
| - | **[[2dkj]] – | + | **[[2dkj]] – TtSHMT + PLP – ''Thermus thermophilus'' <br /> |
| + | **[[8suj] – TtSHMT + PLP derivative<br /> | ||
**[[1kkj]] – GsSHMT + PLP – ''Geobacillus stearothermophilus'' <br /> | **[[1kkj]] – GsSHMT + PLP – ''Geobacillus stearothermophilus'' <br /> | ||
**[[1yjz]], [[2vgs]], [[2vi8]], [[2vmn]], [[2vmp]], [[2vmr]], [[2vmv]], [[2w7d]], [[2w7f]], [[2w7i]] – GsSHMT (mutant) + PLP <br /> | **[[1yjz]], [[2vgs]], [[2vi8]], [[2vmn]], [[2vmp]], [[2vmr]], [[2vmv]], [[2w7d]], [[2w7f]], [[2w7i]] – GsSHMT (mutant) + PLP <br /> | ||
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**[[7e13]] - SHMT + PLP – ''Erigeron canadensis''<br /> | **[[7e13]] - SHMT + PLP – ''Erigeron canadensis''<br /> | ||
**[[4pff]] – PvSHMT + PLP – ''Plasmodium vivax''<br /> | **[[4pff]] – PvSHMT + PLP – ''Plasmodium vivax''<br /> | ||
| + | **[[7ujh]], [[7uji]], [[8dom]] – GmSHMT (mutant) + PLP derivative – ''Glycine max''<br /> | ||
*SHMT binary complex + PLP | *SHMT binary complex + PLP | ||
| + | **[[8a11]] - hSHMT + RNA + PLP derivative – Cryo EM<br /> | ||
**[[1rv3]], [[1rvy]] - rSHMT 1 (mutant) + glycine + PLP <br /> | **[[1rv3]], [[1rvy]] - rSHMT 1 (mutant) + glycine + PLP <br /> | ||
**[[1ls3]] - rSHMT 1 + formyl hydrofolate derivative + PLP derivative <br /> | **[[1ls3]] - rSHMT 1 + formyl hydrofolate derivative + PLP derivative <br /> | ||
| Line 69: | Line 77: | ||
**[[6r8f]] – hSHMT 2 (mutant) in Brisc and Brca1-A complex – Cryo EM <br /> | **[[6r8f]] – hSHMT 2 (mutant) in Brisc and Brca1-A complex – Cryo EM <br /> | ||
**[[6qvg]], [[6qvl]] – hSHMT 2 + PLP + antifolate drug<br /> | **[[6qvg]], [[6qvl]] – hSHMT 2 + PLP + antifolate drug<br /> | ||
| + | **[[8fjt]], [[8fju]] – hSHMT 2 + PLP + Gly + inhibitor<br /> | ||
| + | **[[8fsd]] – sbSHMT + THF derivative + PLP + Gly <br /> | ||
**[[5v7i]] – hSHMT 2 + inhibitor + glycine + PLP <br /> | **[[5v7i]] – hSHMT 2 + inhibitor + glycine + PLP <br /> | ||
| - | **[[6smn]] – AtSHMT 2 + PLP + antifolate drug | + | **[[6smn]] – AtSHMT 2 + PLP + antifolate drug <br /> |
**[[6smw]] – AtSHMT 2 + PLP derivative + antifolate drug<br /> | **[[6smw]] – AtSHMT 2 + PLP derivative + antifolate drug<br /> | ||
**[[6smr]] – AtSHMT 4 + PLP derivative + antifolate drug<br /> | **[[6smr]] – AtSHMT 4 + PLP derivative + antifolate drug<br /> | ||
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**[[4tn4]], [[5gvk]], [[5gvl]], [[5gvm]], [[5gvn]], [[5gvp]], [[5xms]], [[5xmt]], [[5xmu]], [[5xmv]], [[5yfy]], [[5yg0]], [[5yg1]], [[5yg4]] – PvSHMT + inhibitor + PLP derivative <br /> | **[[4tn4]], [[5gvk]], [[5gvl]], [[5gvm]], [[5gvn]], [[5gvp]], [[5xms]], [[5xmt]], [[5xmu]], [[5xmv]], [[5yfy]], [[5yg0]], [[5yg1]], [[5yg4]] – PvSHMT + inhibitor + PLP derivative <br /> | ||
**[[5xmp]], [[5xmq]], [[5xmr]] – PvSHMT (mutant) + inhibitor + PLP derivative <br /> | **[[5xmp]], [[5xmq]], [[5xmr]] – PvSHMT (mutant) + inhibitor + PLP derivative <br /> | ||
| + | **[[7x5o]] – EfSHMT + THF derivative + PLP derivative – ''Enterococcus faecium''<br /> | ||
| + | **[[7v3d]] – EfSHMT + PLP + inhibitor<br /> | ||
| + | **[[7x5n]] – EfSHMT + PLP derivative + inhibitor<br /> | ||
| + | **[[8ssy]] – TtSHMT + PLP derivative + Ser<br /> | ||
| + | **[[8dsk]] – GmSHMT + THF derivative + Gly + PLP derivative <br /> | ||
*SHMT other complexes | *SHMT other complexes | ||
Revision as of 09:50, 15 November 2023
3D structures of Serine hydroxymethyltransferase
Updated on 15-November-2023 {{#tree:id=OrganizedByTopic|openlevels=0|
- SHMT
- 6dk3 – hSHMT 2 – human
- 5x3v – hSHMT 2 (mutant)
- 7pzz – AtSHMT 2 – Arabidopsis thaliana
- 7q00 – AtSHMT 4
- 7qpe – AtSHMT 6
- 7qx8 – AtSHMT 7
- 3gbx – SHMT – Salmonella typhimurium
- 3n0l – SHMT – Campylobacter jejuni
- 3pgy – SHMT + glycine – Staphylococcus aureus
- 4mso – BcSHMT – Burkholderia cenocepacia
- 3ecd – SHMT – Burkholderia pseudomallei
- 4bhd – MjSHMT – Methanocaldococcus jannaschii
- 4p3m – SHMT – Psychromonas ingrahamii
- 4wxb – StSHMT – Streptococcus thermophilus
- 6ti3 – StSHMT (mutant) + threonine
- 5vc2, 6f93 – SHMT – Helicobacter pylori
- 5vmb – SHMT – Acinetobacter baumannii
- 5z0y – SHMT – Pichia pastoris
- 7qcw – SHMT – Pseudomonas chlororaphis <br /
- 6dk3 – hSHMT 2 – human
- SHMT + PLP
- 1bj4 - hSHMT 1 + PLP
- 6fl5 – hSHMT 1 (mutant) + PLP
- 4pvf, 8aql, 8qi7, 8ssj – hSHMT 2 + PLP derivative
- 1cj0, 1rv4, 1rvu – rSHMT 1 (mutant) + PLP – rabbit
- 1eji – SHMT + PLP derivative – mouse
- 6uxh, 6uxi, 6uxk , 6uxl– sbSHMT 8 + PLP derivative – soybean
- 6cd0, 6cd1 – bmSHMT 3 + PLP derivatives - barrel medic
- 2dkj – TtSHMT + PLP – Thermus thermophilus
- [[8suj] – TtSHMT + PLP derivative
- 1kkj – GsSHMT + PLP – Geobacillus stearothermophilus
- 1yjz, 2vgs, 2vi8, 2vmn, 2vmp, 2vmr, 2vmv, 2w7d, 2w7f, 2w7i – GsSHMT (mutant) + PLP
- 3g8m – EcSHMT (mutant) + PLP – Eschericha coli
- 4j5u – SHMT + PLP derivative – Rickettsia rickettsia
- 4n0w - BcSHMT + PLP
- 4uqv - MjSHMT + PLP
- 4o6z – SHMT (mutant) + PLP – Plasmodium falciparum
- 3h7f – MtSHMT + PLP derivative – Mycobacteria tuberculosis
- 6ymd, 6yme, 6ymf – MtSHMT + PLP derivative – Aphanothece halophytica
- 6ti1, 6ti4 – StSHMT (mutant) + PLP derivative
- 7e13 - SHMT + PLP – Erigeron canadensis
- 4pff – PvSHMT + PLP – Plasmodium vivax
- 7ujh, 7uji, 8dom – GmSHMT (mutant) + PLP derivative – Glycine max
- 1bj4 - hSHMT 1 + PLP
- SHMT binary complex + PLP
- 8a11 - hSHMT + RNA + PLP derivative – Cryo EM
- 1rv3, 1rvy - rSHMT 1 (mutant) + glycine + PLP
- 1ls3 - rSHMT 1 + formyl hydrofolate derivative + PLP derivative
- 6uxj - sbSHMT 8 + formyl hydrofolate derivative + PLP
- 6ccz – bmSHMT 3 + selenourea + PLP derivative
- 1dfo – EcSHMT + formyl hydrofolate + PLP derivative
- 1kkp – GsSHMT + serine + PLP
- 1yjy, 2vgu, 2via, 2vmt, 2vmw, 2w7k – GsSHMT (mutant) + serine + PLP
- 2vmx, 2w7g, 2w7l – GsSHMT (mutant) + threonine + PLP
- 1kl1 – GsSHMT + glycine + PLP
- 1yjs, 2vgt, 2vgv, 2vgw, 2vi9, 2vib, 2vmo, 2vmq, 2vms, 2vmu, 2vmz, 2w7e, 2w7h, 2w7j, 2w7m – GsSHMT (mutant) + glycine + PLP
- 4ot8 - BcSHMT + serine + PLP
- 4otl - BcSHMT + glycine + PLP
- 4tn4, 5gvk, 5gvl, 5gvm, 5gvn, 5gvp, 5yfy, 5yg0, 5yg1, 5yfz, 5yg2, 5yg3, 5yg4, 5xms, 5xmt, 5xmu, 5xmv – PvSHMT + inhibitor + PLP derivative – Plasmodium vivax
- 5xmp, 5xmq, 5xmr – PvSHMT (mutant) + inhibitor + PLP derivative
- 4wxf – StSHMT + glycine + PLP derivative
- 6yrw – StSHMT (mutant) + Ser + PLP
- 4wxg – StSHMT + allo-threonine + glycine
- 8a11 - hSHMT + RNA + PLP derivative – Cryo EM
- SHMT ternary complex + PLP
- 6h3c – hSHMT 2 in Brisc and Brca1-A complex – Cryo EM
- 6r8f – hSHMT 2 (mutant) in Brisc and Brca1-A complex – Cryo EM
- 6qvg, 6qvl – hSHMT 2 + PLP + antifolate drug
- 8fjt, 8fju – hSHMT 2 + PLP + Gly + inhibitor
- 8fsd – sbSHMT + THF derivative + PLP + Gly
- 5v7i – hSHMT 2 + inhibitor + glycine + PLP
- 6smn – AtSHMT 2 + PLP + antifolate drug
- 6smw – AtSHMT 2 + PLP derivative + antifolate drug
- 6smr – AtSHMT 4 + PLP derivative + antifolate drug
- 1kl2 – GsSHMT + formyl hydrofolate + glycine + PLP
- 2vmy – GsSHMT (mutant) + formyl hydrofolate + glycine + PLP
- 1eqb - EcSHMT (mutant) + formyl hydrofolate + glycine + PLP
- 6tgh – StSHMT (mutant) + Ser + PLP derivative + pyridine derivative
- 6uld – MtSHMT + Ser + Gly + PLP
- 4tn4, 5gvk, 5gvl, 5gvm, 5gvn, 5gvp, 5xms, 5xmt, 5xmu, 5xmv, 5yfy, 5yg0, 5yg1, 5yg4 – PvSHMT + inhibitor + PLP derivative
- 5xmp, 5xmq, 5xmr – PvSHMT (mutant) + inhibitor + PLP derivative
- 7x5o – EfSHMT + THF derivative + PLP derivative – Enterococcus faecium
- 7v3d – EfSHMT + PLP + inhibitor
- 7x5n – EfSHMT + PLP derivative + inhibitor
- 8ssy – TtSHMT + PLP derivative + Ser
- 8dsk – GmSHMT + THF derivative + Gly + PLP derivative
- 6h3c – hSHMT 2 in Brisc and Brca1-A complex – Cryo EM
- SHMT other complexes
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