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3guc

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Current revision (07:12, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3guc' size='340' side='right'caption='[[3guc]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='3guc' size='340' side='right'caption='[[3guc]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3guc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GUC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GUC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3guc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GUC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GUC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UBA5, UBE1DC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3guc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3guc OCA], [https://pdbe.org/3guc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3guc RCSB], [https://www.ebi.ac.uk/pdbsum/3guc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3guc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3guc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3guc OCA], [https://pdbe.org/3guc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3guc RCSB], [https://www.ebi.ac.uk/pdbsum/3guc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3guc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/UBA5_HUMAN UBA5_HUMAN]] E1-like enzyme which activates UFM1 and SUMO2.<ref>PMID:15071506</ref> <ref>PMID:18442052</ref> <ref>PMID:20368332</ref>
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[https://www.uniprot.org/uniprot/UBA5_HUMAN UBA5_HUMAN] E1-like enzyme which activates UFM1 and SUMO2.<ref>PMID:15071506</ref> <ref>PMID:18442052</ref> <ref>PMID:20368332</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Ubiquitin-fold modifier|Ubiquitin-fold modifier]]
 
*[[3D structures of Ubiquitin activating enzyme|3D structures of Ubiquitin activating enzyme]]
*[[3D structures of Ubiquitin activating enzyme|3D structures of Ubiquitin activating enzyme]]
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bacik, J P]]
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[[Category: Bacik JP]]
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[[Category: Bochkarev, A]]
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[[Category: Bochkarev A]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Dhe-Paganon, S]]
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[[Category: Dhe-Paganon S]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Li, Y]]
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[[Category: Li Y]]
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[[Category: Structural genomic]]
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[[Category: Walker JR]]
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[[Category: Walker, J R]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Atp-binding]]
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[[Category: Rossmann fold]]
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[[Category: Sgc]]
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[[Category: Transferase]]
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[[Category: Ubl conjugation pathway]]
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Current revision

Human Ubiquitin-activating Enzyme 5 in Complex with AMPPNP

PDB ID 3guc

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