This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3h8q
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='3h8q' size='340' side='right'caption='[[3h8q]], [[Resolution|resolution]] 2.21Å' scene=''> | <StructureSection load='3h8q' size='340' side='right'caption='[[3h8q]], [[Resolution|resolution]] 2.21Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3h8q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3h8q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H8Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H8Q FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.21Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h8q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h8q OCA], [https://pdbe.org/3h8q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h8q RCSB], [https://www.ebi.ac.uk/pdbsum/3h8q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h8q ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h8q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h8q OCA], [https://pdbe.org/3h8q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h8q RCSB], [https://www.ebi.ac.uk/pdbsum/3h8q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h8q ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/TRXR3_HUMAN TRXR3_HUMAN] Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components (By similarity).[UniProtKB:Q99MD6] | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 26: | Line 25: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Arrowsmith CH]] | |
| - | [[Category: Arrowsmith | + | [[Category: Bountra C]] |
| - | [[Category: Bountra | + | [[Category: Chaikuad A]] |
| - | [[Category: Chaikuad | + | [[Category: Edwards AM]] |
| - | + | [[Category: Johansson C]] | |
| - | [[Category: Edwards | + | [[Category: Oppermann U]] |
| - | [[Category: Johansson | + | [[Category: Pilka E]] |
| - | [[Category: Oppermann | + | [[Category: Roos AK]] |
| - | [[Category: Pilka | + | [[Category: Ugochukwu E]] |
| - | [[Category: Roos | + | [[Category: Weigelt J]] |
| - | + | [[Category: Yue W]] | |
| - | [[Category: Ugochukwu | + | [[Category: Von Delft F]] |
| - | [[Category: Weigelt | + | |
| - | [[Category: Yue | + | |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of glutaredoxin domain of human thioredoxin reductase 3
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Chaikuad A | Edwards AM | Johansson C | Oppermann U | Pilka E | Roos AK | Ugochukwu E | Weigelt J | Yue W | Von Delft F
