3hbw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:19, 6 September 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3hbw' size='340' side='right'caption='[[3hbw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3hbw' size='340' side='right'caption='[[3hbw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3hbw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HBW FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3hbw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HBW FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1q1u|1q1u]]</div></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FGF13, FHF2, fibroblast growth factor homologous factor 2 (FHF2) ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hbw OCA], [https://pdbe.org/3hbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hbw RCSB], [https://www.ebi.ac.uk/pdbsum/3hbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hbw ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hbw OCA], [https://pdbe.org/3hbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hbw RCSB], [https://www.ebi.ac.uk/pdbsum/3hbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hbw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/FGF13_HUMAN FGF13_HUMAN]] Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus.<ref>PMID:15282281</ref> May regulate voltage-gated sodium channels transport and function.<ref>PMID:15282281</ref> May also play a role in MAPK signaling.<ref>PMID:15282281</ref>
+
[https://www.uniprot.org/uniprot/FGF13_HUMAN FGF13_HUMAN] Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus.<ref>PMID:15282281</ref> May regulate voltage-gated sodium channels transport and function.<ref>PMID:15282281</ref> May also play a role in MAPK signaling.<ref>PMID:15282281</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 36: Line 35:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Mohammadi, M]]
+
[[Category: Mohammadi M]]
-
[[Category: Alternative splicing]]
+
-
[[Category: Beta-trefoil fold]]
+
-
[[Category: Growth factor]]
+
-
[[Category: Hormone]]
+
-
[[Category: Polymorphism]]
+

Current revision

Crystal Structure of Human Fibroblast Growth Factor Homologous Factor 2A (FHF2A), also referred to as Fibroblast Growth Factor 13A (FGF13A)

PDB ID 3hbw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools