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7ryx

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Current revision (16:40, 18 October 2023) (edit) (undo)
 
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<StructureSection load='7ryx' size='340' side='right'caption='[[7ryx]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='7ryx' size='340' side='right'caption='[[7ryx]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7ryx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RYX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7ryx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_YJM789 Saccharomyces cerevisiae YJM789]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RYX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=81H:(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-{5-[4-(trifluoromethoxy)phenyl]pyridin-2-yl}propan-2-ol'>81H</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[5ul0|5ul0]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=81H:(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-{5-[4-(trifluoromethoxy)phenyl]pyridin-2-yl}propan-2-ol'>81H</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ERG11, SCY_2394 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=307796 Baker's yeast])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ryx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ryx OCA], [https://pdbe.org/7ryx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ryx RCSB], [https://www.ebi.ac.uk/pdbsum/7ryx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ryx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ryx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ryx OCA], [https://pdbe.org/7ryx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ryx RCSB], [https://www.ebi.ac.uk/pdbsum/7ryx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ryx ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CP51_YEAST CP51_YEAST] Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7ryx" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7ryx" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Keniya, M V]]
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[[Category: Saccharomyces cerevisiae YJM789]]
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[[Category: Monk, B C]]
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[[Category: Keniya MV]]
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[[Category: Ruma, Y N]]
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[[Category: Monk BC]]
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[[Category: Sagatova, A]]
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[[Category: Ruma YN]]
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[[Category: Tyndall, J D]]
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[[Category: Sagatova A]]
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[[Category: Cyp51]]
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[[Category: Tyndall JD]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Sterol biosynthesis]]
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[[Category: Vt-1129]]
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Current revision

S. CEREVISIAE CYP51 COMPLEXED WITH VT-1129

PDB ID 7ryx

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