3hg6
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='3hg6' size='340' side='right'caption='[[3hg6]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='3hg6' size='340' side='right'caption='[[3hg6]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3hg6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3hg6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lithobates_pipiens Lithobates pipiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HG6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HG6 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hg6 OCA], [https://pdbe.org/3hg6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hg6 RCSB], [https://www.ebi.ac.uk/pdbsum/3hg6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hg6 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hg6 OCA], [https://pdbe.org/3hg6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hg6 RCSB], [https://www.ebi.ac.uk/pdbsum/3hg6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hg6 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RNP30_LITPI RNP30_LITPI] Basic protein with antiproliferative/cytotoxic activity against several tumor cell lines in vitro, as well as antitumor in vivo. It exhibits a ribonuclease-like activity against high molecular weight ribosomal RNA. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 22: | Line 23: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Lithobates pipiens]] |
| - | [[Category: Balbach | + | [[Category: Balbach J]] |
| - | [[Category: Camara-Artigas | + | [[Category: Camara-Artigas A]] |
| - | [[Category: Casares-Atienza | + | [[Category: Casares-Atienza S]] |
| - | [[Category: Garcia-Mira | + | [[Category: Garcia-Mira MM]] |
| - | [[Category: Gavira | + | [[Category: Gavira JA]] |
| - | [[Category: Weininger | + | [[Category: Weininger U]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 07:21, 6 September 2023
Crystal Structure of the Recombinant Onconase from Rana pipiens
| |||||||||||
