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3hks

From Proteopedia

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Current revision (15:50, 1 November 2023) (edit) (undo)
 
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<StructureSection load='3hks' size='340' side='right'caption='[[3hks]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3hks' size='340' side='right'caption='[[3hks]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hks]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HKS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hks]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HKS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">At1G26630.1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hks OCA], [https://pdbe.org/3hks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hks RCSB], [https://www.ebi.ac.uk/pdbsum/3hks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hks ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hks OCA], [https://pdbe.org/3hks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hks RCSB], [https://www.ebi.ac.uk/pdbsum/3hks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hks ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/IF5A2_ARATH IF5A2_ARATH]] The precise role of eIF-5A in protein biosynthesis is not known but it may function as a bimodular protein capable of binding to both RNA and proteins. Regulates cytokinin-mediated root protoxylem specification and represses secifically the expression of AHP6. Regulates the induction of programmed cell death caused by infection with virulent pathogen.<ref>PMID:17513484</ref> <ref>PMID:18633122</ref> <ref>PMID:24163315</ref>
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[https://www.uniprot.org/uniprot/IF5A2_ARATH IF5A2_ARATH] The precise role of eIF-5A in protein biosynthesis is not known but it may function as a bimodular protein capable of binding to both RNA and proteins. Regulates cytokinin-mediated root protoxylem specification and represses secifically the expression of AHP6. Regulates the induction of programmed cell death caused by infection with virulent pathogen.<ref>PMID:17513484</ref> <ref>PMID:18633122</ref> <ref>PMID:24163315</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arath]]
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[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chen, Y X]]
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[[Category: Chen YX]]
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[[Category: He, Y X]]
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[[Category: He YX]]
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[[Category: Jiang, Y L]]
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[[Category: Jiang YL]]
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[[Category: Teng, Y B]]
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[[Category: Teng YB]]
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[[Category: Zhou, C Z]]
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[[Category: Zhou CZ]]
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[[Category: Alternative splicing]]
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[[Category: Beta barrel]]
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[[Category: Hypusine]]
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[[Category: Initiation factor]]
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[[Category: Protein biosynthesis]]
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[[Category: Rna binding protein]]
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[[Category: Translation]]
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Current revision

Crystal structure of eukaryotic translation initiation factor eIF-5A2 from Arabidopsis thaliana

PDB ID 3hks

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