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3hmh

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Current revision (15:50, 1 November 2023) (edit) (undo)
 
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<StructureSection load='3hmh' size='340' side='right'caption='[[3hmh]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='3hmh' size='340' side='right'caption='[[3hmh]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hmh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HMH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hmh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HMH FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3hme|3hme]], [[3hmf|3hmf]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TAF1L ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hmh OCA], [https://pdbe.org/3hmh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hmh RCSB], [https://www.ebi.ac.uk/pdbsum/3hmh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hmh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hmh OCA], [https://pdbe.org/3hmh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hmh RCSB], [https://www.ebi.ac.uk/pdbsum/3hmh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hmh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TAF1L_HUMAN TAF1L_HUMAN]] May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced.<ref>PMID:12217962</ref>
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[https://www.uniprot.org/uniprot/TAF1L_HUMAN TAF1L_HUMAN] May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced.<ref>PMID:12217962</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Delft, F von]]
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[[Category: Edwards A]]
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[[Category: Edwards, A]]
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[[Category: Filippakopoulos P]]
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[[Category: Filippakopoulos, P]]
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[[Category: Keates T]]
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[[Category: Keates, T]]
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[[Category: Knapp S]]
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[[Category: Knapp, S]]
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[[Category: Picaud S]]
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[[Category: Picaud, S]]
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[[Category: Pike ACW]]
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[[Category: Pike, A C.W]]
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[[Category: Weigelt J]]
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[[Category: Structural genomic]]
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[[Category: Zhang Y]]
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[[Category: Weigelt, J]]
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[[Category: Von Delft F]]
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[[Category: Zhang, Y]]
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[[Category: Bromodomain]]
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[[Category: Cell cycle]]
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[[Category: Disulfide bond]]
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[[Category: Dna-binding]]
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[[Category: Mgc134910]]
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[[Category: Nucleus]]
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[[Category: Sgc]]
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[[Category: Taf2a2]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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Current revision

Crystal structure of the second bromodomain of human TBP-associated factor RNA polymerase 1-like (TAF1L)

PDB ID 3hmh

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