7ued

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m (Protected "7ued" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 7ued is ON HOLD until Paper Publication
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==Crystal structure of full length mesothelin bound with MORAb-009 Fab==
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<StructureSection load='7ued' size='340' side='right'caption='[[7ued]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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Authors: Zhan, J., Esser, L., Lin, D., Tang, W.K., Xia, D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7ued]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UED OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UED FirstGlance]. <br>
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Description: Crystal structure of full length mesothelin bound with MORAb-009 Fab
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ued FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ued OCA], [https://pdbe.org/7ued PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ued RCSB], [https://www.ebi.ac.uk/pdbsum/7ued PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ued ProSAT]</span></td></tr>
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[[Category: Lin, D]]
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</table>
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[[Category: Tang, W.K]]
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== Disease ==
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[[Category: Xia, D]]
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[https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer.
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[[Category: Esser, L]]
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== Function ==
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[[Category: Zhan, J]]
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[https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Membrane-anchored forms may play a role in cellular adhesion.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref> Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Esser L]]
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[[Category: Lin D]]
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[[Category: Tang WK]]
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[[Category: Xia D]]
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[[Category: Zhan J]]

Revision as of 11:15, 1 February 2023

Crystal structure of full length mesothelin bound with MORAb-009 Fab

PDB ID 7ued

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OCA

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