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7ued
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of full length mesothelin bound with MORAb-009 Fab== | |
| - | + | <StructureSection load='7ued' size='340' side='right'caption='[[7ued]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7ued]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UED OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UED FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ued FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ued OCA], [https://pdbe.org/7ued PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ued RCSB], [https://www.ebi.ac.uk/pdbsum/7ued PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ued ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Disease == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer. |
| - | [[Category: | + | == Function == |
| - | [[Category: Zhan | + | [https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Membrane-anchored forms may play a role in cellular adhesion.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref> Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Esser L]] | ||
| + | [[Category: Lin D]] | ||
| + | [[Category: Tang WK]] | ||
| + | [[Category: Xia D]] | ||
| + | [[Category: Zhan J]] | ||
Revision as of 11:15, 1 February 2023
Crystal structure of full length mesothelin bound with MORAb-009 Fab
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Categories: Homo sapiens | Large Structures | Mus musculus | Esser L | Lin D | Tang WK | Xia D | Zhan J
