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7em5
From Proteopedia
(Difference between revisions)
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==Crystal structure of the PI5P4Kbeta F205L-XTP complex== | ==Crystal structure of the PI5P4Kbeta F205L-XTP complex== | ||
| - | <StructureSection load='7em5' size='340' side='right'caption='[[7em5]]' scene=''> | + | <StructureSection load='7em5' size='340' side='right'caption='[[7em5]], [[Resolution|resolution]] 2.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EM5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EM5 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7em5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EM5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EM5 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7em5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7em5 OCA], [https://pdbe.org/7em5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7em5 RCSB], [https://www.ebi.ac.uk/pdbsum/7em5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7em5 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CZC:[(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl+phosphono+hydrogen+phosphate'>CZC</scene>, <scene name='pdbligand=CZF:[[(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+phosphono+hydrogen+phosphate'>CZF</scene></td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/1-phosphatidylinositol-5-phosphate_4-kinase 1-phosphatidylinositol-5-phosphate 4-kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.149 2.7.1.149] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7em5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7em5 OCA], [https://pdbe.org/7em5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7em5 RCSB], [https://www.ebi.ac.uk/pdbsum/7em5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7em5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/PI42B_HUMAN PI42B_HUMAN]] Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.<ref>PMID:9038203</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: 1-phosphatidylinositol-5-phosphate 4-kinase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Senda M]] | + | [[Category: Senda, M]] |
| - | [[Category: Senda T]] | + | [[Category: Senda, T]] |
| + | [[Category: Lipid kinase]] | ||
| + | [[Category: Phosphoinositide signaling]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 10:30, 6 April 2022
Crystal structure of the PI5P4Kbeta F205L-XTP complex
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