7q05

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====
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==Crystal structure of TPADO in complex with TPA==
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<StructureSection load='7q05' size='340' side='right'caption='[[7q05]]' scene=''>
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<StructureSection load='7q05' size='340' side='right'caption='[[7q05]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7q05]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Comamonas_sp. Comamonas sp.] and [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Q05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Q05 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q05 OCA], [https://pdbe.org/7q05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q05 RCSB], [https://www.ebi.ac.uk/pdbsum/7q05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q05 ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UB7:terephthalic+acid'>UB7</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q05 OCA], [https://pdbe.org/7q05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q05 RCSB], [https://www.ebi.ac.uk/pdbsum/7q05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q05 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/TPDB1_COMSP TPDB1_COMSP]] Component of the terephthalate 1,2-dioxygenase multicomponent enzyme system which catalyzes the dioxygenation of terephthalate (TER/TPA) to 1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylic acid (DCD). It can also use 2,5-dicarboxypyridine (PDC) and 1,4-napthalenedicarboxylic acid (NDC) as substrates, and preferentially uses NADPH which is the physiological electron donor.<ref>PMID:16517628</ref> <ref>PMID:18776687</ref> <ref>PMID:7961417</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Comamonas sp]]
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[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: DuBois JL]]
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[[Category: Kincannon WM]]
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[[Category: McGeehan JE]]
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[[Category: Zahn M]]

Revision as of 16:48, 7 September 2022

Crystal structure of TPADO in complex with TPA

PDB ID 7q05

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