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2vle

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Current revision (15:24, 13 December 2023) (edit) (undo)
 
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<StructureSection load='2vle' size='340' side='right'caption='[[2vle]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='2vle' size='340' side='right'caption='[[2vle]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2vle]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1of7 1of7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VLE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VLE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2vle]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1of7 1of7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VLE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VLE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DZN:DAIDZIN'>DZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1cw3|1cw3]], [[1nzw|1nzw]], [[1nzx|1nzx]], [[1nzz|1nzz]], [[1o00|1o00]], [[1o01|1o01]], [[1o04|1o04]], [[1o02|1o02]], [[1o05|1o05]], [[1zum|1zum]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DZN:DAIDZIN'>DZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(NAD(+)) Aldehyde dehydrogenase (NAD(+))], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.3 1.2.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vle OCA], [https://pdbe.org/2vle PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vle RCSB], [https://www.ebi.ac.uk/pdbsum/2vle PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vle ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vle OCA], [https://pdbe.org/2vle PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vle RCSB], [https://www.ebi.ac.uk/pdbsum/2vle PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vle ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Gao, G Y]]
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[[Category: Gao GY]]
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[[Category: Johnson, L N]]
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[[Category: Johnson LN]]
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[[Category: Keung, W M]]
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[[Category: Keung WM]]
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[[Category: Lowe, E D]]
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[[Category: Lowe ED]]
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[[Category: Acetylation]]
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[[Category: Alcohol abuse]]
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[[Category: Aldehyde dehydrogenase]]
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[[Category: Daidzin]]
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[[Category: Mitochondrion]]
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[[Category: Nad]]
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[[Category: Oxidoreductase]]
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[[Category: Polymorphism]]
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[[Category: Transit peptide]]
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Current revision

The structure of daidzin, a naturally occurring anti alcohol- addiction agent, in complex with human mitochondrial aldehyde dehydrogenase

PDB ID 2vle

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