2vsg

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vsg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VSG FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vsg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VSG FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1vsg|1vsg]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vsg OCA], [https://pdbe.org/2vsg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vsg RCSB], [https://www.ebi.ac.uk/pdbsum/2vsg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vsg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vsg OCA], [https://pdbe.org/2vsg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vsg RCSB], [https://www.ebi.ac.uk/pdbsum/2vsg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vsg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/VSI4_TRYBB VSI4_TRYBB]] VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
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[https://www.uniprot.org/uniprot/VSI4_TRYBB VSI4_TRYBB] VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
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[[Category: Blum, M L]]
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[[Category: Blum ML]]
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[[Category: Down, J A]]
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[[Category: Down JA]]
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[[Category: Freymann, D M]]
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[[Category: Freymann DM]]
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[[Category: Metcalf, P]]
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[[Category: Metcalf P]]
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[[Category: Wiley, D C]]
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[[Category: Wiley DC]]
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[[Category: Antigenic variation]]
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[[Category: Membrane protein]]
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[[Category: Trypanosome]]
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[[Category: Vsg]]
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Revision as of 00:23, 28 December 2023

A Structural Motif in the Variant Surface Glycoproteins of Trypanosoma Brucei

PDB ID 2vsg

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