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7x0a

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'''Unreleased structure'''
 
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The entry 7x0a is ON HOLD until Paper Publication
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==Cryo-EM structure of human TRiC-NPP state==
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<StructureSection load='7x0a' size='340' side='right'caption='[[7x0a]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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Authors: Cong, Y., Liu, C.X.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7x0a]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X0A FirstGlance]. <br>
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Description: Cryo-EM structure of human TRiC-NPP state
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x0a OCA], [https://pdbe.org/7x0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x0a RCSB], [https://www.ebi.ac.uk/pdbsum/7x0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x0a ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Cong, Y]]
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== Function ==
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[[Category: Liu, C.X]]
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[https://www.uniprot.org/uniprot/TCPA_HUMAN TCPA_HUMAN] Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444). As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable).<ref>PMID:20080638</ref> <ref>PMID:25467444</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Cong Y]]
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[[Category: Liu CX]]

Revision as of 20:27, 12 April 2023

Cryo-EM structure of human TRiC-NPP state

PDB ID 7x0a

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