This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7eil
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==BRD4-BD1 in complex with LT-909-110== | ==BRD4-BD1 in complex with LT-909-110== | ||
| - | <StructureSection load='7eil' size='340' side='right'caption='[[7eil]]' scene=''> | + | <StructureSection load='7eil' size='340' side='right'caption='[[7eil]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EIL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EIL FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7eil]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EIL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EIL FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7eil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7eil OCA], [https://pdbe.org/7eil PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7eil RCSB], [https://www.ebi.ac.uk/pdbsum/7eil PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7eil ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=909:N-[4-[4-ethanoyl-5-methyl-2-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-pyrrol-3-yl]phenyl]ethanamide'>909</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7eil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7eil OCA], [https://pdbe.org/7eil PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7eil RCSB], [https://www.ebi.ac.uk/pdbsum/7eil PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7eil ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity). | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Chen Y]] | [[Category: Chen Y]] | ||
Revision as of 06:22, 26 October 2022
BRD4-BD1 in complex with LT-909-110
| |||||||||||
Categories: Homo sapiens | Large Structures | Chen Y | Kong B | Tang W | Zheng W | Zhu J
