2wal

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Current revision (10:10, 9 May 2024) (edit) (undo)
 
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<StructureSection load='2wal' size='340' side='right'caption='[[2wal]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='2wal' size='340' side='right'caption='[[2wal]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WAL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2wal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WAL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wal OCA], [https://pdbe.org/2wal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wal RCSB], [https://www.ebi.ac.uk/pdbsum/2wal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wal ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wal OCA], [https://pdbe.org/2wal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wal RCSB], [https://www.ebi.ac.uk/pdbsum/2wal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wal ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/GA45G_HUMAN GA45G_HUMAN]] Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
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[https://www.uniprot.org/uniprot/GA45G_HUMAN GA45G_HUMAN] Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bhattacharya, S]]
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[[Category: Bhattacharya S]]
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[[Category: Buessow, K]]
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[[Category: Buessow K]]
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[[Category: Goetz, F]]
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[[Category: Goetz F]]
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[[Category: Heinemann, U]]
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[[Category: Heinemann U]]
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[[Category: Mueller, J J]]
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[[Category: Mueller JJ]]
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[[Category: Quedenau, C]]
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[[Category: Quedenau C]]
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[[Category: Roske, Y]]
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[[Category: Roske Y]]
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[[Category: Turnbull, A P]]
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[[Category: Turnbull AP]]
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[[Category: Apoptosis]]
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[[Category: Cdc2/cyclinb1]]
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[[Category: Cell-cycle arrest]]
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[[Category: Developmental protein]]
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[[Category: Differentiation]]
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[[Category: Dna damage]]
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[[Category: G2/m phase]]
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[[Category: Gadd]]
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Current revision

Crystal Structure of human GADD45gamma

PDB ID 2wal

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