2wbk

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Current revision (15:50, 13 December 2023) (edit) (undo)
 
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<StructureSection load='2wbk' size='340' side='right'caption='[[2wbk]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='2wbk' size='340' side='right'caption='[[2wbk]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wbk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bactn Bactn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WBK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2wbk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron_VPI-5482 Bacteroides thetaiotaomicron VPI-5482]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WBK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=M2F:2,4-DINITROPHENYL+2-DEOXY-2-FLUORO-BETA-D-MANNOPYRANOSIDE'>M2F</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2vqt|2vqt]], [[2vot|2vot]], [[2vl4|2vl4]], [[2vqu|2vqu]], [[2vo5|2vo5]], [[2je8|2je8]], [[2vr4|2vr4]], [[2vjx|2vjx]], [[2vmf|2vmf]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=M2F:2,4-DINITROPHENYL+2-DEOXY-2-FLUORO-BETA-D-MANNOPYRANOSIDE'>M2F</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-mannosidase Beta-mannosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.25 3.2.1.25] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbk OCA], [https://pdbe.org/2wbk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wbk RCSB], [https://www.ebi.ac.uk/pdbsum/2wbk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wbk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbk OCA], [https://pdbe.org/2wbk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wbk RCSB], [https://www.ebi.ac.uk/pdbsum/2wbk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wbk ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8AAK6_BACTN Q8AAK6_BACTN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bactn]]
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[[Category: Bacteroides thetaiotaomicron VPI-5482]]
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[[Category: Beta-mannosidase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Davies, G J]]
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[[Category: Davies GJ]]
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[[Category: Gilbert, H J]]
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[[Category: Gilbert HJ]]
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[[Category: Offen, W A]]
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[[Category: Offen WA]]
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[[Category: Withers, S G]]
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[[Category: Withers SG]]
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[[Category: Zechel, D L]]
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[[Category: Zechel DL]]
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[[Category: Beta-mannoside]]
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[[Category: Conformational itinerary]]
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[[Category: Glycoside hydrolase]]
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[[Category: Hydrolase]]
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[[Category: Mannosidase]]
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[[Category: Michaelis complex]]
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Current revision

Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis

PDB ID 2wbk

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