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2wnf

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Current revision (16:04, 13 December 2023) (edit) (undo)
 
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<StructureSection load='2wnf' size='340' side='right'caption='[[2wnf]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
<StructureSection load='2wnf' size='340' side='right'caption='[[2wnf]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wnf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WNF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2wnf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WNF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CG3:HYDROXY(2-HYDROXYPHENYL)OXOAMMONIUM'>CG3</scene>, <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=CG3:HYDROXY(2-HYDROXYPHENYL)OXOAMMONIUM'>CG3</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PRD_900084:Thomsen-Friedenreich+antigen'>PRD_900084</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wnb|2wnb]], [[2wml|2wml]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-galactoside_alpha-2,3-sialyltransferase Beta-galactoside alpha-2,3-sialyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.99.4 2.4.99.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnf OCA], [https://pdbe.org/2wnf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wnf RCSB], [https://www.ebi.ac.uk/pdbsum/2wnf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wnf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnf OCA], [https://pdbe.org/2wnf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wnf RCSB], [https://www.ebi.ac.uk/pdbsum/2wnf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wnf ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SIA4A_PIG SIA4A_PIG]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-galactoside alpha-2,3-sialyltransferase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pig]]
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[[Category: Sus scrofa]]
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[[Category: Raikic, B]]
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[[Category: Raikic B]]
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[[Category: Rao, F V]]
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[[Category: Rao FV]]
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[[Category: Rich, J R]]
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[[Category: Rich JR]]
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[[Category: Strynadka, N C.J]]
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[[Category: Strynadka NCJ]]
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[[Category: Wakarchuk, W W]]
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[[Category: Wakarchuk WW]]
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[[Category: Withers, S G]]
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[[Category: Withers SG]]
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[[Category: Disulfide bond]]
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[[Category: Glycoprotein]]
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[[Category: Glycosyltransferase]]
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[[Category: Golgi apparatus]]
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[[Category: Membrane]]
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[[Category: Secreted]]
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[[Category: Sialic acid]]
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[[Category: Sialyltransferase]]
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[[Category: Signal-anchor]]
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[[Category: Transferase]]
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[[Category: Transmembrane]]
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Current revision

Crystal Structure of a Mammalian Sialyltransferase in complex with Gal-beta-1-3GalNAc-ortho-nitrophenol

PDB ID 2wnf

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OCA

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