7x4z
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Rhodostomin ARGDWP mutant== | |
| - | + | <StructureSection load='7x4z' size='340' side='right'caption='[[7x4z]], [[Resolution|resolution]] 1.48Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7x4z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X4Z FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x4z OCA], [https://pdbe.org/7x4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x4z RCSB], [https://www.ebi.ac.uk/pdbsum/7x4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x4z ProSAT]</span></td></tr> |
| - | [[Category: Chang | + | </table> |
| - | [[Category: Chuang | + | == Function == |
| + | [https://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Calloselasma rhodostoma]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chang YT]] | ||
| + | [[Category: Chuang WJ]] | ||
Revision as of 07:27, 8 March 2023
Crystal structure of Rhodostomin ARGDWP mutant
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