4qgm

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Current revision (17:31, 20 September 2023) (edit) (undo)
 
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<StructureSection load='4qgm' size='340' side='right'caption='[[4qgm]], [[Resolution|resolution]] 2.97&Aring;' scene=''>
<StructureSection load='4qgm' size='340' side='right'caption='[[4qgm]], [[Resolution|resolution]] 2.97&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4qgm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_ames_"ancestor" Bacillus anthracis ames "ancestor"]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QGM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4qgm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._'Ames_Ancestor' Bacillus anthracis str. 'Ames Ancestor']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QGM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.97&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4qgl|4qgl]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAS3949, BA_4258, GBAA4258, GBAA_4258, mtnD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=261594 Bacillus anthracis Ames "Ancestor"])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgm OCA], [https://pdbe.org/4qgm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qgm RCSB], [https://www.ebi.ac.uk/pdbsum/4qgm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgm OCA], [https://pdbe.org/4qgm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qgm RCSB], [https://www.ebi.ac.uk/pdbsum/4qgm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MTND_BACAN MTND_BACAN]] Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity).
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[https://www.uniprot.org/uniprot/MTND_BACAN MTND_BACAN] Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity).
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus anthracis ames ancestor]]
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[[Category: Bacillus anthracis str. 'Ames Ancestor']]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Anderson, W F]]
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[[Category: Anderson WF]]
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[[Category: Borowski, T]]
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[[Category: Borowski T]]
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[[Category: Structural genomic]]
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[[Category: Chruszcz M]]
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[[Category: Chruszcz, M]]
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[[Category: Cooper DR]]
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[[Category: Cooper, D R]]
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[[Category: Milaczewska AM]]
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[[Category: Milaczewska, A M]]
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[[Category: Minor W]]
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[[Category: Minor, W]]
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[[Category: Shabalin IG]]
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[[Category: Shabalin, I G]]
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[[Category: Csgid]]
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[[Category: Iron binding]]
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[[Category: Oxidoreductase]]
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[[Category: Rmlc-like cupin]]
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Current revision

Acireductone dioxygenase from Bacillus anthracis with cadmium ion in active center

PDB ID 4qgm

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