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4yea

From Proteopedia

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Current revision (07:57, 27 September 2023) (edit) (undo)
 
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<StructureSection load='4yea' size='340' side='right'caption='[[4yea]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
<StructureSection load='4yea' size='340' side='right'caption='[[4yea]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4yea]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YEA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YEA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4yea]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YEA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YEA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3iwx|3iwx]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ATOX1, HAH1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yea OCA], [https://pdbe.org/4yea PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yea RCSB], [https://www.ebi.ac.uk/pdbsum/4yea PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yea ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yea OCA], [https://pdbe.org/4yea PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yea RCSB], [https://www.ebi.ac.uk/pdbsum/4yea PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yea ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ATOX1_HUMAN ATOX1_HUMAN]] Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense.
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[https://www.uniprot.org/uniprot/ATOX1_HUMAN ATOX1_HUMAN] Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Dauter, Z]]
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[[Category: Dauter Z]]
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[[Category: Jaskolski, M]]
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[[Category: Jaskolski M]]
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[[Category: Minor, W]]
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[[Category: Minor W]]
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[[Category: Shabalin, I G]]
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[[Category: Shabalin IG]]
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[[Category: Wlodawer, A]]
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[[Category: Wlodawer A]]
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[[Category: Cisplatin]]
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[[Category: Metal transport]]
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[[Category: Metal-binding]]
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[[Category: Platinum]]
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[[Category: Re-refinement of 3iwx]]
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Current revision

Crystal structure of cisplatin bound to a human copper chaperone (dimer) - new refinement

PDB ID 4yea

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