This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


7m6u

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (16:06, 18 October 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='7m6u' size='340' side='right'caption='[[7m6u]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
<StructureSection load='7m6u' size='340' side='right'caption='[[7m6u]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[7m6u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pses6 Pses6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7M6U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7M6U FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[7m6u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._RS-16 Pseudomonas sp. RS-16] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7M6U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7M6U FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1cg2|1cg2]], [[6xj5|6xj5]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cpg2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=312 PSES6])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glutamate_carboxypeptidase Glutamate carboxypeptidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.11 3.4.17.11] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m6u OCA], [https://pdbe.org/7m6u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m6u RCSB], [https://www.ebi.ac.uk/pdbsum/7m6u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m6u ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m6u OCA], [https://pdbe.org/7m6u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m6u RCSB], [https://www.ebi.ac.uk/pdbsum/7m6u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m6u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/CBPG_PSES6 CBPG_PSES6]] Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity.
+
[https://www.uniprot.org/uniprot/CBPG_PSES6 CBPG_PSES6] Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 25: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Glutamate carboxypeptidase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Pses6]]
+
[[Category: Pseudomonas sp. RS-16]]
-
[[Category: Khare, S D]]
+
[[Category: Synthetic construct]]
-
[[Category: Yachnin, B J]]
+
[[Category: Khare SD]]
-
[[Category: Circular permutation]]
+
[[Category: Yachnin BJ]]
-
[[Category: Directed enzyme-prodrug therapy]]
+
-
[[Category: Enzyme design]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Methotrexate]]
+
-
[[Category: Pro-enzyme]]
+

Current revision

Crystal structure of a circular permutation and computationally designed pro-enzyme of carboxypeptidase G2

PDB ID 7m6u

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7m6u"
Personal tools