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1ys7

From Proteopedia

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Current revision (08:12, 25 October 2023) (edit) (undo)
 
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<StructureSection load='1ys7' size='340' side='right'caption='[[1ys7]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
<StructureSection load='1ys7' size='340' side='right'caption='[[1ys7]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ys7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YS7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YS7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ys7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YS7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YS7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ys3|1ys3]], [[1ys6|1ys6]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ys7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ys7 OCA], [https://pdbe.org/1ys7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ys7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ys7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ys7 ProSAT], [https://www.topsan.org/Proteins/XMTB/1ys7 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ys7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ys7 OCA], [https://pdbe.org/1ys7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ys7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ys7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ys7 ProSAT], [https://www.topsan.org/Proteins/XMTB/1ys7 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PRRA_MYCTU PRRA_MYCTU]] Member of the two-component regulatory system PrrB/PrrA. Involved specifically in early intracellular multiplication of Mycobacterium.
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[https://www.uniprot.org/uniprot/PRRA_MYCTU PRRA_MYCTU] Member of the two-component regulatory system PrrB/PrrA. Involved specifically in early intracellular multiplication of Mycobacterium.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Nowak, E]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Panjikar, S]]
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[[Category: Nowak E]]
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[[Category: Tucker, P]]
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[[Category: Panjikar S]]
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[[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project]]
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[[Category: Tucker P]]
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[[Category: Dna binding domain]]
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[[Category: Mycobacterium tuberculosis structural proteomics project]]
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[[Category: Phosphorylation]]
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[[Category: Response regulator]]
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[[Category: Structural genomic]]
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[[Category: Transcription regulator]]
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[[Category: Xmtb]]
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Current revision

Crystal structure of the response regulator protein prrA complexed with Mg2+

PDB ID 1ys7

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