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7s5a

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Current revision (16:44, 18 October 2023) (edit) (undo)
 
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<StructureSection load='7s5a' size='340' side='right'caption='[[7s5a]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
<StructureSection load='7s5a' size='340' side='right'caption='[[7s5a]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7s5a]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7S5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7S5A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7s5a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7S5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7S5A FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7s5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7s5a OCA], [https://pdbe.org/7s5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7s5a RCSB], [https://www.ebi.ac.uk/pdbsum/7s5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7s5a ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.37&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7s5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7s5a OCA], [https://pdbe.org/7s5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7s5a RCSB], [https://www.ebi.ac.uk/pdbsum/7s5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7s5a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CCL8_HUMAN CCL8_HUMAN]] Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.<ref>PMID:9558113</ref>
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[https://www.uniprot.org/uniprot/CCL8_HUMAN CCL8_HUMAN] Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.<ref>PMID:9558113</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7s5a" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7s5a" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Monocyte chemoattractant protein|Monocyte chemoattractant protein]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Aryal, P]]
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[[Category: Aryal P]]
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[[Category: Bhusal, R P]]
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[[Category: Bhusal RP]]
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[[Category: Devkota, S R]]
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[[Category: Devkota SR]]
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[[Category: Stone, M J]]
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[[Category: Stone MJ]]
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[[Category: Wilce, M C.J]]
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[[Category: Wilce MCJ]]
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[[Category: Cc chemokine]]
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[[Category: Cytokine]]
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Current revision

Crystal structure of human chemokine CCL8

PDB ID 7s5a

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OCA

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