This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ifz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:57, 1 November 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3ifz' size='340' side='right'caption='[[3ifz]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='3ifz' size='340' side='right'caption='[[3ifz]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3ifz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IFZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IFZ FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3ifz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IFZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IFZ FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ab4|1ab4]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gyrA, MT0006, MTCY10H4.04, Rv0006 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ifz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ifz OCA], [https://pdbe.org/3ifz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ifz RCSB], [https://www.ebi.ac.uk/pdbsum/3ifz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ifz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ifz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ifz OCA], [https://pdbe.org/3ifz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ifz RCSB], [https://www.ebi.ac.uk/pdbsum/3ifz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ifz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/GYRA_MYCTU GYRA_MYCTU]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.
+
[https://www.uniprot.org/uniprot/GYRA_MYCTU GYRA_MYCTU] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 39: Line 37:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Myctu]]
+
[[Category: Mycobacterium tuberculosis H37Rv]]
-
[[Category: Aubry, A]]
+
[[Category: Aubry A]]
-
[[Category: Delarue, M]]
+
[[Category: Delarue M]]
-
[[Category: Mayer, C]]
+
[[Category: Mayer C]]
-
[[Category: Piton, J]]
+
[[Category: Piton J]]
-
[[Category: Antibiotic resistance]]
+
-
[[Category: Atp-binding]]
+
-
[[Category: Breakage and reunion domain]]
+
-
[[Category: Dna binding site]]
+
-
[[Category: Dna gyrase]]
+
-
[[Category: Dna-binding]]
+
-
[[Category: Gyra]]
+
-
[[Category: Isomerase]]
+
-
[[Category: Nucleotide-binding]]
+
-
[[Category: Quinolone binding site]]
+
-
[[Category: Topoisomerase]]
+
-
[[Category: Tuberculosis]]
+
-
[[Category: Type ii topoisomerase]]
+

Current revision

crystal structure of the first part of the Mycobacterium tuberculosis DNA gyrase reaction core: the breakage and reunion domain at 2.7 A resolution

PDB ID 3ifz

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3ifz"
Personal tools